The Relationship Between Doppler Parameters and Perinatal Outcomes in Postterm Pregnancies

Amaç: Uzamış gebeliklerde doppler ultrasonografi bulguları ile perinatal sonuçlar arasındaki ilişkiyi incelemek amaçlandı. Gereç ve Yöntem: Bu çalışmaya 37-41 gebelik haftası arasındaki 51 (kontrol grubu), ≥41 gebelik haftasındaki 50 hasta (çalışma grubu) dahil edildi. Renkli doppler ultrasonografide umblikal arter ve orta serebral artere ait akım paternleri değerlendirilerek doppler indeksleri ölçüldü. Bu damarlarda akımı değerlendirmek için, pulsatilite indeksi, rezistivite indeksi ve sistol/diastol oranı ölçüldü. Bulgular: Uzamış gebeliklerde, kontrol grubuna göre, umblikal arter rezistivite indeks değeri daha yüksek, pulsatilite indeks değeri daha düşük bulundu. Uzamış gebeliklerde ölçülen orta serebral arter rezistivite indeks ortanca değeri kontrol grubuna göre anlamlı derecede daha düşüktü ve bu, beyin için oluşturulan koruma mekanizması lehine bir bulgu olarak değerlendirildi. Orta serebral arter rezistivite indeks / umblikal arter rezistivite indeks ortanca değeri çalışma grubunda (1.11) kontrol grubununkine (1.25) göre istatistiksel olarak daha küçüktü, nitekim uzamış gebelikler için kötü perinatal sonuç %64 sıklıkla kontrol grubuna göre istatistiksel olarak anlamlı derecede daha fazla bulundu. Uzamış gebeliklerde kötü perinatal sonucu öngörmede orta serebral arter rezistivite indeks / umblikal arter rezistivite indeks oranı

Uzamış Gebeliklerde Doppler Ultrasonografi Bulguları ile Perinatal Sonuçlar Arasındaki İlişki

Aim: The aim of the study is to identify the relationship between doppler parameters and perinatal outcomes in post-term pregnancies. Material and Method: 101 pregnant women (37-41 weeks, control group; n:51 and ≥41 weeks, study group, n:50) were included in the study. We performed umblical artery and middle cerebral artery blood flow velocity waveform (pulsatility index, resistivity index, and systole/diastole ratio) analyses for our patients. Results: The mean value of the umbilical artery resistivity index was significantly higher in the study group than the control group while the mean value of the umbilical artery pulsatility index was significantly lower in the study group. The middle cerebral artery resistivity index was significantly lower in the study group, which was consistent with preferantial perfusion of the brain. We also found decreased ratios of middle cerebral artery resistivity index in umblical artery resistivity index in the study group (1.11) compared with the control group (1.25). These findings can be interpreted in favor of worse perinatal outcomes in the study group while the increased adverse perinatal outcome rates (%64) in the study group supports this view. The ratio of middle cerebral artery resistivity index to umblical artery resistivity index

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  • 1. 2. 3. 4. 5. 6. 7. 8. 9. Chazan D. Niemiec KT. Filipp E. Postterm Pregnancy - Importance of this problem in modern obstetrics. Ginekol Pol 1996;67:148-56.
  • Leppert PC. Anatomy and Physiology of Cervical Ripening. Clin Obstet Gynecol 1995;38:267-79.
  • Ganstrom L. Ekman G. Ulmsten U. Myometrial Activity After Local Application of Prostaglandin E2 for Cervical Ripening and Term Labor Induction. Am J Obstet Gynecol 1990;162:691-4.
  • Harma M. Postterm gebelik. Çiçek MN. Çelik C. Akyürek C. Haberal A. editör. Kadın Hastalıkları ve Doğum Bilgisi. 2. Baskı. Ankara: Güneş Kitabevi; 2004. p. 483-6. Spelaccy WN. Scott JR. Disaia PJ. Hammond CB. Postdate Pregnancy. In: Scott JR. Gibbs RS. Karlan BY. Haney AF. eds. Danforths Obstetrics & Gynecology. 7th edition. Philedelphia: W.B. Saunders Company; 1994. p. 32-5.
  • Halloren DR. Cheng YW. Wall TC. Macanes GA. Caughey AB. Effect of maternal weight on postterm delivery. J Perinatol 2012;32:85-90.
  • Owe KM. Nystad W. Skjaerven R. Stigum H. Bo K. Exercise during pregnancy and the gestational age distribution. Med Sci Sports Exerc 2012;44:1067-74.
  • Bel-Ange A. Harlev A. Weintraub AV. Sheiner E. Waiting for postterm in healty women is an accident waiting to happen. J Matern Fetal Neonatal Med 2013;26:779-82.
  • Fisher RL. Kuhlman KA. Depp R. Wapner RJ. Doppler evaluation of umblical and uterin arcuate arteries in the postdate pregnancies. Obstet and Gynecol 1991;78:363-72. 10.
  • Kurjak A. Alfrevic Z. Miljan M. Conventional and color Doppler in the assessment of fetal and maternal circulation. Ultrasound Med Biol 1998;14:337-54. 11.
  • Olofsson P. Saldeen P. Marsal K. Aaociation between a low umblical artery pulsatility index and fetal distress in labor in very prolonged pregnancies. Eur J of Obstet and Gynec 1997;73:23-9. 12.
  • Nicholson S. Nimrod C. Doppler assessment of pregnancy. In: Rumack CM. Wilson SR. Levine D. eds. Diagnostic Ultrasound. 3rd edition. St Louis: Mosby 1991. p. 955-70. 13.
  • Nakai A. Oya A. Accuracy and reproducibility of ultrasound measurements in obstetric management. Gynecol Obstet Invest 2002;54:31-6. 14.
  • Fleischer AC. Goldstein RB. Bruner JP. Worrell JA. Doppler sonography in obstetric and gynecology. In: Callen PW eds. Ultrasonography in Obstetrics and Gynecology. 3rd edition. Philedelphia: W.B. Saunders Company; 1994. p. 503-23. 15.
  • Wladimiroff JW. Huisman TWA. Stewart PA. Normal fetal arterial and venous flow-velocity waveforms in early and late gestation. In: Jaffe R. Warsof SL. eds. Color Doppler Imaging in Obstetrics and Gynecology. New York: McGraw- Hill; 1992. p. 155-73. 16.
  • James D. Steer J. Weiner C. Gonik B. Prolonged pregnancy. In: James D. Steer PJ. Weiner CP. Gonik B. Growther C. Robson S. eds. High Risk Pregnancy Management Options. 4th edition. St. Louis: Elsevier Saunders; 2005. p. 1376-82. 17.
  • Doherty L. Norwitz ER. Prolonged pregnancy: when should we intervene. Curr Opin Obstet Gynecol 2008;20:519-27. 18.
  • Hermu WA. Verhoeven CS. Mol BW. de Wolf GS. Fiedeldeij CA. Comparison of induction of labor and expectant management in postterm pregnancy. J Midwifery Womens Health 2009;54:351-6.
  • Received/Başvuru: 28.04.2014,Correspondence/İletişim Cemile DAYANGAN SAYAN Kırıkkale Yuksek Ihtisas Research and Training Hospital, Department of Obstetircs and Gynaecology, KIRIKKALE, TURKEY E-mail: c.dayangan-sayan@hotmail.com 19. Mandruzzato et al. Guidelines for the management of postterm pregnancy. J Perinat Med 2010;38:111-9. 20.
  • Palacio M. Fıgueras L. Zamora A. Reference ranges for umblical and middle serebral artery pulsatility index and cerebroplacental ratio in prolonged pregnancies. Ultrasound Obstet Gynecol 2004;24:647-53. 21.
  • Ogunyemi D. Stanley R. Lynch C. Edwards D. Fukushima T. Umblical artery velocimetry in predicting perinatal outcome with intrapartum fetal distress. Obstet Gynecol 1992;80:377-80. 22.
  • Mogren I.Stenlund H.Högberg U. Recurrence of prolonged pregnancy. Int J Epidemiol 1999;28:253-7. 23.
  • Kofinas AD. Denry M. Nelson LH. Meis PJ. Swain M. Uterine and umbi lical artery flow velocity waveform analysis in pregnancies comp licated by chronic hypertension or preeclampsia. South Med J 1990;83:150-5. 24.
  • Schulman H. Fleischer A. Farmakides G. Bracero L. Rochelson B. Grun-feld L. Development of uterine artery compliance in pregnancy as detec ted by Doppler ultrasound. Am J Obstet Gynecol 1986;155:1031-6. 25.
  • Jörn H.Funk A.Fendel H. Doppler Ultrasound in postterm pregnancy. Z Geburtslife Perinatol 1993;53:603-8. 26.
  • Arabin B.Becker R. Mohnhaupt A. Vollert W. Weitzel HK. Prediction of fetal distres and poor outcome in prolonged pregnancy using Doppler Ultrasound and fetal heart rate monitoring combined with stres tests. Fetal Diagn Ther 1994;9:1-6. 27.
  • Urban R. Lemancewicz A. Urban J. Alifier M. Kretowsko M. The Doppler cerebroplasental ratios and perinatal outcome in postterm pregnancy. Ginekol Pol 2000;71:317-21.
İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi-Cover
  • ISSN: 1300-1744
  • Yayın Aralığı: 4
  • Yayıncı: İnönü Üniversitesi Tıp Fakültesi
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