Amniyotik Band Senromu: Olgu Sunumu

Amniotik band sendromu, amnion zarının erken rüptürüne bağlı gelişen, geniş bir fetal anomali spektrumuna sebep olur. ABS prevelansı 1/1200 ile 1/15000 arasında değişebilmekte, spontan abortuslarda 1/56'ya kadar çıkabilmektedir. Bu sendromda geniş bir dizi malformasyon ortaya çıkabilmesine karşılık ekstremiteler sıklıkla tutulmuştur. Prognoz anomalilerin şiddetine ve iç organ tutulumuna bağlıdır. Burada 24 yaşında, ilk gebeliği olan kadında, intraterin defekt nedeni ile tıbbi tahliyeye neden olan amniotik band sendromu olgusu sunulmuştur. Annede herhangi bir hastalık, ilaç kullanımı veya travma öyküsü yoktu. Fetal otopside 14-15. gestasyonel haftada olan fetusda çeşitli ekstremite anomalileri tespit edildi. ABS özellikle ekstemite anomalileriyle birlikte giden fetal anomalilerin ayırıcı tanısında akılda tutulmalıdır.

Amniotic Band Syndrome: A Case Report

Amniotic band syndrome causes a wide spectrum of fetal anomalies secondary to the early rupture of the amnion. Its prevalence ranges between one in 1200 and 15000 live-born and reaches one in 56 in stillbirths. Although a wide range of malformations can occur in this syndrome, extremities are frequently involved. The prognosis depends on the severity of the abnormalities and the involvement of internal organs. Herein a case of amniotic band syndrome which caused medical evacuation for intauterin defect in a 24 years old primigravid woman was submitted. There was no history of maternal illness, drug use or trauma. In the fetal autopsy, the fetus was in the 14-15 th gestationalweek, and several extremity anomalies were found. Amniotic Band Syndrome should be kept in mind in the differential diagnosis of fetal anomalies, especially with extremity involvement.

PDF

___

Deborah J, Gersell, Frederick TK. Diseas of the placenta.In:Kurman RJ editor. Blaustein's Pathology of the Female Genital Tract, 5th ed. New York: Springer - Verlag; 2002. p. 1155-6.
Bodamer OAF, Popek EJ, Bacino C. Atypical presentetion of amniotic band sequence. Am J Med Genet 2001;100-2.
Pauli RM, Lebovitz RM, Meyer RD. Familial recurrence of terminal transverse defects of the arm. Clin Genet 1985;27:555-63.
İvit TH, Köksal A, Çukurova K, Keklik A, Yıldız A, Tezcan B. Amniotik band sendromu: Bir olgu sunumu. Türkiye Klinikleri Jinekol Obst 2003;13:399-400.
Klausek DK, Bamforth S. Amnion rupture sequence in previable fetuses. Am J Med Genet 1988;31:63-73.
Tanaka O, Koh T, Otani H. Amniogenic band anomalies in fifth month fetus and in a newborn from maternal oophorectomy during early pregnancy. Teratology 1986;33:187-93.
Api M, Görgen H, Fıçıcı C, Yorgancı C. Amniotik band sendromu: Bir olgu sunumu. Perinatoloji Dergisi 1993;1:231-5.
Orpin R. Amniochorionic mesoblastic fibrous strings and amniotic bands. Am J obstet Gynecol 1965;91:65-75.
Chen H. Amniotic Band Syndrome.In: Chen Harold , editor. Atlas of Genetic Diagnosis and Counseling. 1st edition. New Jersey: Humana Pres; 2006.p.42-9.
Dyer JA, Chamlin S. Acquired raised bands of infancy: Association with amniotic bands. Pediatr Dermatol 2005;22:346-9.
Orioli IM, Ribeiro MG, Castilla EE. Clinical and epidemiological studies of amniotic deformity, adhesion, and mutilation (ADAM) sequence in a south American population. Am J Med Genet 2003;118 A:135-45.
Kohn G. The amniotica band syndrome . A possible complication of amniocentesis. Prenat Diagn 1987;7:303- 5.
Keswani SG, Johnson MP, Adzick NS, Hori S, Howell LJ, Wilson RD, et al. In utero limb salvage: Fetoscopic release of amniotic bands for threatened limb amputation. J Pediatr Surg 2003;38:848-51.
Pedersen TK, Thomsen SG. Spontaneous resolution of amniotic bands. Ultrasound Obstet Gynecol 2001;18:673-4.