Ozlem TEKŞAM, Ramazan OZDEMİRL, Benan BAYRAKCIZ

Acute Amitriptyline Poisoning in Childhood: Experience of Single Center

Amaç: Yüksek doz amitriptilin çocuklarda ciddi ilaç zehirlenmesinin en yaygın nedenlerinden biridir. Bu makalede, amitriptilin zehirlenmesi olan 126 çocuğun demografik Özellikleri ve klinik bulguları gözden geçirilmiştir. Gereç ve Yöntem: Ocak 1986 ve Mart 2011 tarihleri arasında amitriptilin zehirlenmesi nedeniyle Çocuk Yoğun Bakım Ünitesine yatırılan O-- 16 yaş arası çocukların tıbbi kayıtları retrospektif olarak değerlendirildi. Bulgular: Son yıllarda amitriptilin zehirlenmelerinin artmış olduğu görüldü. Zehirlenmelerin %62.7'si kaza nedenli, %37.3'ü ise intihar amaçlı idi. Kaza nedenli zehirlenmelerin yaş ortalaması 2.931.4 yaş, intihar amaçlı zehirlenmelerin yaş ortalaması 14.231.9 yaştı (p

Çocukluk Çağında Akut Amitriptilin Zehirlenmesi: Tek Merkezin Deneyimi

Objective: High—dose amitriptyline is common cause of childhood poisoning. The aim of this study was to evaluate the demographic and clinical characteristics of 126 children who presented with amitriptyline poisoning. Material and Methods: The medical records of children who were admitted to the Pediatric Intensive Care Unit for amitriptyline poisoning between January 1986 and March 2011 were retrospectively evaluated. Results: High—dose amitriptyline is common cause of childhood poisoning. An increase in the number of cases of amitriptyline poisoning was observed in recent years, with 62.7% of all cases being accidental whereas 37.3% of cases were attempted suicides. The mean age of accidental cases of poisoning was 2.931.4 years compared to 14.231 .9 years for suicidal cases (p

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