Kalsiyum Oksalat Monohidrat Kristal Büyümesine Karahindiba (Taraxacum Officinale) Bitkisinin Etkisinin İncelenmesi

Böbrek taşları günümüzde önemini koruyan, yaygın bir hastalıktır. Böbrek taşı, aşırı doygun ürin içerisinde kalsiyum oksalat monohidrat kristallerinin renal papillalardaki epitel hücrelerde çekirdeklenme, büyüme ve çökme aşamalarından oluşan bir kristalizasyon prosesidir. İlerleyen teknolojiye rağmen böbrek taşlarının tekrarlanabilirliğinin yüksek olması ile tıbbi ve cerrahi tedavilerin yüksek risk faktörleri taşıması geleneksel yöntemlerde yeni arayışlara sebep olmuştur. Bu çalışmada, biyomineralizasyon açısından oldukça önemli olan kalsiyum oksalat kristalizasyonuna doğal katkı maddesi olarak Karahindiba (Taraxacum officinale) bitki ekstraktının in vitro koşullarda etkileri incelenmiştir

Investigation of the Effect of Dandelion Plant (Taraxacum Officinale) on Calcium Oxalate Monohydrate Crystal Growth

The formation of kidney stones is a common diasese. It has accepted that the formation of kidney stones is a process that consist of nucleation, growth and aggregation of calcium oxalate monohydrate crystals on epithelial cells at renal papillae in super saturated urine. In spite of the technological developments, the high recurrence rate of kidney stone formation and the risk factors of all available surgical and medical treatments for kidney stone disease cause new researches in traditional methods. In this study, the effects of dandelion (Taraxacum officinale) plant extract as a natural additive on crystallization of calcium oxalate, which have great importance in biomineralization, were investigated in vitro

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