PSÖDOMİKSOMA PERİTONEİ'NEYE YOL AÇAN SENKRON APENDİKS VE OVER TÜMÖRÜ

Psödomiksoma peritonei, peritoneal kavitede aşırı miktarda müsinöz materyal birikimi ile karakterize bir durumdur. Apendiks müsinöz kistadenomu ve ovaryan müsinöz tümör birlikteliği sık olsa da apendiks adenokarsinoidi ile nadiren eş zamanlı olarak görülürler. Karın ağrısı şikayetiyle jinekoloji polikliniğine başvuran 72 yaşında kadın hastada ultrasonografide sağ over kaynaklı kistik ve solid alanları izlenen kitle saptanması üzerine total histerektomi+bilateral salpingoooferektomi+ omentektomi+apendektomi yapıldı. Apendikste müsinöz kistadenom ve adenokarsinoid tümör, sağ overde ise borderline müsinöz tümör tespit edildi. Bu üç tümörün birlikteliği nadir bir durumdur.

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Pseudomyxoma peritonei is a condition characterized by the accumulation of excessive amounts of mucinous material in the peritoneal cavity. Althought appendiceal mucinous cystadenoma and mucinous ovarian tumor are often seen together, the coexistence with adenocarcinoid of the appendix is rare. A-72-year-old female patient was admitted to our gynecology outpatient clinic with abdominal pain complaint. Ultrasonography showed cystic right ovarian mass with solid fields. Total hysterectomy + bilateral salpingooopherectomy + omentectomy + appendectomy were performed. Mucinous cystadenoma of the appendix, adenocarcinoid tumor and ovarian borderline mucinous tumor coexistance is a rare combination

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  • Kojimahara T, Nakahara K, Shoji T, Sugiyama T, Takano T,
  • Yaegashi N, et al. Identifying prognostic factors in Japanese
  • women with pseudomyxomaperitonei: a retrospective clinicopathological
  • study of theTohoku Gynecologic Cancer Unit.
  • Tohoku J ExpMed. 2011;223(2):91-6.
  • Lee KR, Scully RE. Mucinous tumors of the ovary: a
  • clinicopathologic study of 196 borderline tumors (of intestinal
  • type) and carcinomas, including an evaluation of 11 cases
  • with ‘pseudomyxomaperitonei’ Am J Surg Pathol.
  • ;24:1447–1464.
  • Lee JK, Song SH, Kim I, Lee KH, Kim BG, Kim JW, et al.
  • Retrospective multicenter study of a clinicopathologic analysis
  • of pseudomyxoma peritonei associated with ovarian tumors
  • (KGOG 3005) Int J Gynecol Cancer. 2008;18:916–920.
  • Van Ruth S, Acherman YI, van de Vijver MJ, Hart AA,
  • Verwaal VJ, Zoetmulder FA. Pseudomyxomaperitonei: a
  • review of 62 cases. Eur J Surg Oncol. 2003;29:682–688.
  • Dong Y, Li T, Zou W, Liang Y. Pseudomyxomaperitonei:
  • report of 11 cases with a literature review. Zhonghua
  • Binglixue Zazhi. 2002;31:522–525.
  • Scully RE, Young RH, Clement PB. Tumors of the ovary,
  • maldeveloped gonads, fallopian tube, and broad ligament: Atlas
  • of tumorpathology. Armed Forces İnstitute Of Pathology,
  • ;81-105..
  • Riddel RH, Petras RE, Williams GT, Sobin LH. Tumors of
  • theintestines, Atlas of tumorpathology. Armed Forces
  • İnstitute Of Pathology, 2003;241-248.
  • Mahteme H, Sugarbaker PH. Treatment of peritoneal
  • carcinomatosis from adenocarcinoid of appendiceal origin. Bri
  • J Surg. 2004;91:1168-1173.
  • Edmonds P, Merino MJ, Livolsi VA, Duray PH.
  • Adenocarcinoid (mucinouscarcinoid) of theappendix.
  • Gastroenterology. 1984;86:302-309.
  • Capella C, Rosa SL, Uccella S, Billo P, Cornaggia M. Mixed
  • endocrine- exocrinetumours of thegastrointestinal tract. Semin
  • Diagn Pathol .2000;17:91-103.
  • Klöppel G, Perren A, Heitz PU. The Gastroenteropancreatic
  • Neuroendocrine Cell Systemand Its Tumors: The WHO
  • Classification. Ann NY Acad Sci. 2004;1014:13-27.
  • Rindi G, Klöppel G. Endocrine tumors of the gut and
  • pancreas tumor biology and classification.
  • Neuroendocrinology. 2004;80:12-15.
  • Volante M, Rindi G, Papotti M. The grey zone between
  • pure (neuro)endocrine and non-(neuro)endocrine tumours: a
  • comment on concepts and classification of mixed exocrineendocrine
  • neoplasms. Virchows Arch. 2006;449:499-506.
  • Velusamy A, Saw S, Gossage J, Bailey S, Schofield J. Combined
  • adenocarcinoid and mucinous cystadenoma of the appendix:
  • a case report. A Journal of Medical Case Reports.
  • ;3:28.