Mortaliteyle Sonuçlanan Geç Başlangıçlı Warfarin Kaynaklı Cilt Nekrozu Olgusu

Warfarine bağlı cilt nekrozu, warfarin tedavisinin nadir görülen bir komplikasyonudur ve yüksek mortalite ile ilişkilidir. Burada 5,5 yıl önce atriyal fibrilasyon ve geçirilmiş mitral kapak cerrahisi nedeniyle warfarin tedavisine başlanan 53 yaşında kadın hastada ölümcül seyreden warfarine bağlı cilt nekrozu olgusu sunulmaktadır. Warfarin kullanan hastalar cilt lezyonları ile başvurduklarında warfarine bağlı cilt nekrozu açısından değerlendirilmelidir. Erken tanı, ilacın erken kesilmesi ve destek tedavisine erken başlanması hayat kurtarıcı olabilir.

Anahtar Kelimeler:

cilt nekrozu, geç başlangıçlı, warfarin

A Case Of Late-onset Warfarin Induced Skin Necrosis Resulting In Mortality

Warfarin-induced skin necrosis is a rare complication of warfarin therapy and is associated with high mortality. Here, we present a case of warfarin-induced skin necrosis, that was fatal in a 53-year-old female patient who was started on warfarin treatment 5.5 years ago due to atrial fibrillation and previous mitral valve surgery. Patients using warfarin should be evaluated for warfarin-induced skin necrosis when they present with skin lesions. Early diagnosis, early discontinuation of the drug, early initiation of supportive treatment can be life-saving.

Keywords:

late onset, skin necrosis, warfarin,

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