Pseudo-Meigs Sendromu ile Başvuran Struma Ovarii: Bir Olgu Sunumu ve Literatürün Gözden Geçirilmesi

Pseudo-Meigs sendromu, over fibromu dışındaki pelvik tümörlerin eşlik ettiği asites ve plevral efüzyon ile karakterize klinik bir durumdur. Struma ovarii, bu sendroma yol açabilen bir tümördür ve matür kistik teratomun bir çeşididir. Pseudo-Meigs sendromu ile sunulduğunda malign over tümörleri, peritonit karsinomatozis ve malign plevral efüzyon ile karıştırılabilmesi nedeniyle önemlidir. Bir diğer önemli faktör ise tümörün çıkarılmasından sonra asites ve plevral efüzyonun kaybolması ve semptomların hızla gerilemesidir. Eşlik eden asites ve yüksek CA-125 değerleri ile struma ovarii çok nadir görülür. Bu yazıda over malignitesi ön tanısı ile opere edilen ve postoperatif dönemde semptom ve şikayetleri hızla düzelen, histopatolojik struma ovarii tanısıyla opere edilen 53 yaşında bir hasta sunuldu. Postmenopozal dönemde CA125 yüksekliği, over kitlesi, asit, plevral efüzyon varlığında yalancı Meigs sendromu ayırıcı tanılar arasında düşünülmelidir. Ayrıca fertilite potansiyelini henüz kaybetmemiş ancak sitolojik incelemesi malignite açısından olumsuz sonuç veren hastalarda, özellikle açıklanamayan asit ve plevral efüzyon varlığında nadiren de olsa Pseudo-Meigs sendromu ayırıcı tanılar arasında düşünülmelidir.

Struma Ovarii Presented With Pseudo-Meigs’ Syndrome: A CaseReport and Review of The Literature

Pseudo-Meigs' syndrome is a clinical condition characterized by ascites and pleural effusion, accompanied by pelvic tumors other than ovarian fibroma. Struma ovarii is a tumor that can lead to this syndrome and is a variant of mature cystic teratoma. When presented with Pseudo-Meigs’ syndrome, it is important because it can be confused with malignant ovarian tumors, peritonitis carcinomatosis, and malignant pleural effusion. Another important factor is the disappearance of the ascites and pleural effusion and rapid regression of symptoms after the removal of the tumor. Accompanying ascites and high CA-125 values with struma ovarii ​​is very rarely seen. In the present report, a 53-year-old patient with histopathological diagnosis of struma ovarii who had been operated because of presumptive diagnosis of ovarian malignancy and whose symptoms and complaints rapidly resolved during the postoperative period was presented. Pseudo-Meigs’ syndrome should be considered among differential diagnoses in the presence of CA125 elevation, ovarian mass, ascites, pleural effusion in postmenopausal period. In addition, Pseudo-Meigs’ syndrome, though rarely, should be considered among differential diagnoses in patients who have not yet lost their fertility potential but whose cytological examination yielded negative results in terms of malignancy, especially in the presence of unexplained ascites and pleural effusion.

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