Meltem VURAL, Cemal BES, Kadriye Kart YAŞAR, Deniz YILMAZ, Ferit BABAŞOV

Bruselloz Tedavisi Altında Gelişen Sistemik Lupus Eritematozus

İlaca bağlı lupus eritematozus, ilaç kullanımına bağlı ortaya çıkan ve ilacın kesilmesi sonrasında klinik bulguların gerilemesi ile karakterize bir bozukluktur. İlaç kaynaklı lupus eritematozusun klinik ve laboratuar bulguları sistemik lupus eritematozusun (SLE) bulguları ile benzerdir. Doksisiklin, rifampisin veya streptomisin ile tetiklenen SLE son derece nadirdir. Bu yazıda doksisiklin, rifampisin veya streptomisin tedavisine bağlı artralji, lökopeni, lenfopeni ve plevral efüzyon gelişen bir olgu sunulmuştur.

Anahtar Kelimeler:

Bruselloz, Doksisiklin, Rifampisin, Streptomisin

Systemic Lupus Erythematosus Developed Under The Brucellosis Therapy

Drug-induced lupus erythematosus is a disorder which is temporally related to continuous drug exposure and clinical findings resolve upon discontinuation of the offending drug. Its clinical and laboratory findings are similar to systemic lupus erythematosus (SLE). SLE induced by doxycycline, rifampicin or streptomycin are extremely rare. We present the case of a patient who developed arthralgia, leucopenia, lymphopenia and pleural effusion due to the doxycycline, rifampicin or streptomycin drugs treatment.

Keywords:

Brucellosis, Doxycycline, Rifampicin, Streptomycin,

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