Azmi TELEFONCU, Burcu OKUTUCU, Karsten HAUPT

Molecularly imprinted polymer for serotonin recognition

Developing of new techniques for detecting important biologic molecules are one of the aims of molecular imprinting. Serotonin (5-hydroxytryptamine) is a biogenic amine that acts as a neurotransmitter in the central and peripheral nervous systems. It is present in a variety of organisms, ranging from humans to species such as worms that have primitive nervous systems, and mediates a variety of physiological responses in distinct cell types. Serotonin is one of the indolic compound which has a clinical importance. Serotonin imprinted polymers were synthesized by using different functional monomers. Best results were taken with 2-(trifluoromethyl) acrylic acid and methacrylamide. The binding capacities in different solvents were evaluated. The specifity of polymer was tested by real blood sample.

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