PANKREAS KANSERİ TANILI HASTALARDA ENDOSKOPİK ULTRASON EŞLİĞİNDE ÇÖLYAK NÖROLİZ AĞRI TEDAVİSİ İÇİN KULLANILAN ALKOL VE FENOLÜN ETKİLERİNİN KARŞILATIRILMASI: RETROSPEKTİF ANALİZ

Amaç: Çalışmada amacımız EUS rehberliğinde uygulanan çölyak pleksus nöroliz işleminde kullanılan etanol ve fenolün ağrı skorları ve komplikasyonlar üzerine etkinliklerini karşılaştırmaktır. Gereç Yöntem: Ocak 2009 ve Haziran 2022 tarihleri arasında endoskopi biriminde sedasyon altında EUS (endoskopik ultrasonografi) rehberliğinde çöliyak nöroliz uygulanan 28 hasta dahil edildi. Pankreas kanseri tanılı hastaların ağrı tedavisi için uygulanan EUS rehberliğinde çölyak nöroliz girişiminin verilerini retrospektif olarak inceledik Bulgular: Alkol grubundaki hastaların ağrı skorları daha düşük saptanmıştır. Sonuç: Alkol ve fenol bazlı nörolitik teknikler karşılaştırıldığında alkol grubunda daha iyi analjezik etki elde edilmiştir

Comparison of the Effects of Alcohol and Phenol Used for Celiac Neurolysis with Endoscopic Ultrasound in Patients with Pancreas Cancer: Retrospective Analysis

Objective: In this study we aimed to compare the efficacy of ethanol and phenol used in the EUS-guided celiac plexus neurolysis procedure on pain scores and complications. Material and Methods: Between January 2009 and June 2022, 28 patients who underwent celiac neurolysis underwent sedation via EUS (endoscopic ultrasonography) guidance in the endoscopy unit were included. We retrospectively analyzed the data of the EUS-guided celiac neurolysis procedures for pain management of patients with pancreatic cancer. Results: Patients in the alcohol group had lower pain scores. Conclusion: When alcohol and phenol-based neurolytic techniques were compared, better analgesic effect was obtained in the alcohol group.

___

  • 1. Schmidt-Hansen M, Bennett MI, Arnold S, Bromham N, Hilgart JS. oxycodone for cancer-related pain _ Cochrane Database System Rev [Internet]. 2017 Aug 22 [ cited 2022 Jul 12];8(8). available from : https://pubmed.ncbi.nlm.nih.gov/28829910/
  • 2. Kanno Y, Koshita S, Masu K, Ogawa T, Kusunose H, Murabayashi T, et al. Efficacy of EUS- guided celiac plexus neurolysis compared with medication alone for unresectable pancreatic cancer in the oxycodone / fentanyl era : a prospective randomized control study _ gastrointestinal Endoscopy . 2020;92(1):120–30.
  • 3. Asif AA, Walayat SK, Bechtold ML, Revanur V, Puli SR. EUS guided celiac plexus neurolysis for pain in pancreatic cancer patients – a meta- analysis and systematic review . vol . 11, Journal of Community hospital internal medicine Perspectives . 2021.p. 536–42.
  • 4. Teoh AYB, Dhir V, Kida M, Yasuda I, Jin ZD, Seo DW, et al. consensus guidelines on the optimal management in interventional EUS procedures : results from the Asian EUS group RAND/UCLA expert panel. Gout [Internet]. 2018 [ cited 2022 Jul 12];67(7):1209–28. available from : https://pubmed.ncbi.nlm.nih.gov/29463614/
  • 5. Ishiwatari H, Hayashi T, Yoshida M, Ono M, Masuko H, Sato T, et al. Phenol-based endoscopic ultrasound-guided celiac plexus neurolysis for East Asian alcohol-intolerant upper gastrointestinal cancer patients : A pilot study . World Journal of Gastroenterology . 2014;20(30):10512–7.
  • 6. Haaga JR, Kori SH, Eastwood DW, Borkowski GP. improved technique for CT - guided celiac ganglia block . AJR Am J Roentgenol [Internet]. 1984 [ cited 2022 Jul 13];142(6):1201–4. available from : https://pubmed.ncbi.nlm.nih.gov/6609609/
  • 7. Kappis M. Erfahrungen myth localanasthesie bei bauchoperation _ verb dtsch ges chir . 1914;43:87 –9.
  • 8. Mercadante S, Nicosia F. Celiac plexus block : a reappraisal . Reg Anesth pain Med [Internet]. 1998 [ cited 2022 Jul 13];23(1):37–48. available from : https://pubmed.ncbi.nlm.nih.gov/9552777/
  • 9. Leblanc JK, Al- Haddad M, McHenry L, Sherman S, Juan M, McGreevy K, et al. A prospective , randomized study of EUS- guided celiac plexus neurolysis for pancreatic cancer : one injection or two ? gastrointestinal Endosc [Internet]. 2011 Dec [ cited 2022 Jul 13];74(6):1300–7. available from : https://pubmed.ncbi.nlm.nih.gov/22000795/
  • 10. Téllez-Ávila FI, Romano-Munive AF, de Jesús Herrera-Esquivel J, Ramírez-Luna MA. Central is as effective as bilateral endoscopic ultrasound-guided celiac plexus neurolysis in patients with unresectable pancreatic cancer . endosc ultrasound [Internet]. 2013 [ cited 2022 Jul 13];2(3):153–6. available from : https://pubmed.ncbi.nlm.nih.gov/24949384/
  • 11. de Cicco M, Matovic M, Bortolussi R, Coran F, Fantin D, Fabiani F, et al. celiac plexus block : injectate spread and pain relief in patients with regional anatomic distortion _ Anesthesiology [Internet]. 2001 [ cited 2022 Jul 13];94(4):561–5. available from : https://pubmed.ncbi.nlm.nih.gov/11379673/
  • 12. Nagels W, Pease N, Bekkering G, Cools F, Dobbels P. Celiac plexus neurolysis for abdominal cancer pain : a systematic review . pain Med [Internet]. 2013 [ cited 2022 Jul 13];14(8):1140–63. available from : https://pubmed.ncbi.nlm.nih.gov/23802777/
  • 13. Sakamoto H, Kitano M, Kamata K, Komaki T, Imai H, Chikugo T, et al. EUS guided broad plexus neurolysis over the superior mesenteric artery using a 25-gauge needle . Am J Gastroenterol [Internet]. 2010 Dec [ cited 2022 Jul 13];105(12):2599–606. available from : https://pubmed.ncbi.nlm.nih.gov/20823834/
  • 14. Zhang CL, Zhang TJ, Guo YN, Yang LQ, He MW, Shi JZ, et al. Effect of neurolytic celiac plexus block guided by computerized tomography on pancreatic cancer pain _ dig External Sci [Internet]. 2008 Mar [ cited 2022 Jul 13];53(3):856–60. available from : https://pubmed.ncbi.nlm.nih.gov/17676392/
  • 15. Wong GY, Schroeder DR, Carns PE, Wilson JL, Martin DP, Kinney MO, et al. Effect of neurolytic celiac plexus block on pain relief , quality of life, and survival in patients with unresectable pancreatic cancer : a randomized controlled trial . JAMA [Internet]. 2004 Mar 3 [ cited 2022 Jul 13];291(9):1092–9. available from : https://pubmed.ncbi.nlm.nih.gov/14996778/
  • 16. Kawamata M, Ishitani K, Ishikawa K, Sasaki H, Ota K, Omote K, et al. Comparison between celiac plexus block and morphine treatment on quality of life in patients with pancreatic cancer pain _ Pain [Internet]. 1996 [ cited 2022 Jul 13];64(3):597–602. available from : https://pubmed.ncbi.nlm.nih.gov/8783327/
  • 17. Bang JY, Sutton B, Hawes RH, Varadarajulu S. EUS- guided celiac ganglion radiofrequency ablation versus celiac plexus neurolysis for palliation of pain in pancreatic cancer : a randomized controlled trial ( with videos ). gastrointestinal Endoscopy [Internet]. 2019;89(1):58-66.e3. available from : https://doi.org/10.1016/j.gie.2018.08.005
  • 18. Ishiwatari H, Hayashi T, Yoshida M, Ono M, Sato T, Miyanishi K, et al. EUS guided celiac plexus neurolysis by using highly viscous phenol-glycerol as a neurolytic agent ( with video). gastrointestinal Endoscopy [Internet]. 2015;81(2):479–83. available from : http://dx.doi.org/10.1016/j.gie.2014.10.031
  • 19. O'Toole TM, Schmulewitz N. Complication rates of EUS- guided celiac plexus blockade and neurolysis : results of a large case series . Endoscopy [Internet]. 2009 [ cited 2022 Jul 13];41(7):593–7. available from : https://pubmed.ncbi.nlm.nih.gov/19588286/
  • 20. Alvarez-Sánchez MV, Jenssen C, Faiss S, Napoléon B. Interventional endoscopic ultrasonography : an overview of safety and costs . Surg Endosc [Internet]. 2014 [ cited 2022 Jul 13];28(3):712–34. available from : https://pubmed.ncbi.nlm.nih.gov/24196551/
  • 21. Sahai A v., Lemelin V, Lam E, Paquin SC. Central vs. bilateral endoscopic ultrasound-guided celiac plexus block or neurolysis : a comparative study of short term effect . Am J Gastroenterol [Internet]. 2009 Feb [ cited 2022 Jul 13];104(2):326–9. available from : https://pubmed.ncbi.nlm.nih.gov/19174816/
  • 22. Minaga K, Kitano M, Imai H, Miyata T, Kudo M. Acute spinal cord infarction after EUS- guided celiac plexus neurolysis _ gastrointestinal Endosc [Internet]. 2016 May 1 [ cited 2022 Jul 13];83(5):1039–40. available from : https://pubmed.ncbi.nlm.nih.gov/26551729/
Genel Tıp Dergisi-Cover
  • ISSN: 2602-3741
  • Yayın Aralığı: Yılda 6 Sayı
  • Başlangıç: 1997
  • Yayıncı: SELÇUK ÜNİVERSİTESİ > TIP FAKÜLTESİ
Sayıdaki Diğer Makaleler

Minimal İnvaziv Atriyal Septal Defekt Kapatılması: Tek Merkez Deneyimi

Mehmet ÇELİK, Asım Çağrı GÜNAYDIN, Mehmet ÖZÜLKÜ

İNTRAKRANİYAL PATOLOJİLER VE ENDOKRİN SONUÇLARI: TEK ÇOCUK ENDOKRİNOLOJİ MERKEZİ TECRÜBESİ

Ülkü GÜL ŞİRAZ

Friedreich Ataksisi Olan Hastaların Skolyoz Cerrahisinde Anestezi Yönetimi: Dört Olgu Sunumu

Şemsi Mustafa AKSOY, Ayşe LAFÇI, Ercan BAL, Muhammed KÖSE

Baş Ağrısında Nörolojik Muayenesi Normal Olan Hastalar İçin Beyin MRG Gerekli midir?

Fatih ÇANKAL, Dilara PATAT

Fibromiyalji Sendromlu Kadın Hastaların Partnerlerinin Yaşam Kalitesi, Uyku Bozuklukları ve Psikolojik Durumları

Lutfiye PARLAK, Halim YILMAZ, Selman PARLAK

Renal Transplantasyon Hastalarında Transplantasyon Öncesi Ve Sonrası Kardiyovasküler Sistemin Değerlendirilmesi Ve Beyin Natriüretik Peptit İle İlişkisi

Banu KADIOĞLU YILMAZ, Enver HASANOĞLU, Sevcan BAKKALOĞLU, Ayşe Deniz OĞUZ, Hatice PAŞAOĞLU, Ayşe Fıtnat TUNCEL BAHAR

Anterior Vaginal Wall Endometrioma: Case Report

Sıtkı ÖZBİLGEÇ, Emine TÜREN DEMİR, Arife Ebru TAŞCI, Şeyma ÇİÇEK, Havvanur ÇALIŞKAN, Ali ACAR

Tıp Fakültesi Öğrencilerinin HPV, HPV Aşısı ve Rahim Ağzı Kanseri Hakkında Bilgi, Tutum ve Davranışları: Bir Tıp Fakültesinde Anket Çalışması

Mursel DUZOVA, Sefa KÜÇÜKKINALI, Amır EMAMVIRDI, Ahmet Tarık KOZAK, Hacer İlkay GENÇ, Hasan Ali CIRIK, Şahsenem Beyzanur ŞAHİNKAYA, Ahmet Mert ULUCAN

PANKREAS KANSERİ TANILI HASTALARDA ENDOSKOPİK ULTRASON EŞLİĞİNDE ÇÖLYAK NÖROLİZ AĞRI TEDAVİSİ İÇİN KULLANILAN ALKOL VE FENOLÜN ETKİLERİNİN KARŞILATIRILMASI: RETROSPEKTİF ANALİZ

Uğur ÖZGÜRBÜZ, Birzat Emre GÖLBOYU

Donmuş fil hortumu prosedürü hakkında araştırma eğilimleri ve en çok alıntı yapılan makaleler

Serpil ŞAHİN