Hasan GÜÇER, Recep BEDİR, Remzi Adnan AKDOĞAN, Ahmet Fikret YÜCEL

Kolorektal karsinomda heterotopik kemik oluşumu: Olgu sunumu

Heterotopik kemik oluşumu (kemik metaplazisi) gastrointestinal sistemde nadir olarak görülür. Genellikle kolorektal benign veya malign epitelyal tümörler ve sıklıkla müsinöz adenokarsinom ile birliktelik gösterir. Gastrointestinal sistemde rektum en sık tutulan bölgedir. Kemik metaplazisinin patogenezi bilinmemekte fakat fibroblastların metaplazisi sonucu oluştuğu düşünülmektedir. Yetmiş üç yaşında erkek hastada gözlenen primer kolorektal adenokarsinomda heterotopik kemik oluşumu irdelenmiştir.

Heterotopic bone formation in colorectal carcinoma: A case report

Heterotopic bone formation (osseous metaplasia) is rarely seen in the gastrointestinal tract. It usually occurs in the colorectum in association with benign or malignant epithelial tumors, and most often with mucinous adenocarcinoma. The rectum is the most common location of ossification in the gastrointestinal tract. The pathogenesis of the heterotopic ossification is unknown, but it is probably the result of metaplasia of fibroblasts. We present a case of heterotopic bone formation in a primary rectal adenocarcinoma which was observed in a 73-year-old man.

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