Hong Thien VAN, Thi Ngan Ha BUI, Van Son LE, Van Dat DOAN, Yen Hoa MAI, Minh Nhat Hao NGUYEN, Tan Viet PHAM, Pham Tan Quoc LE

Chemical Composition and Antibacterial Activities of Ethanol Extract of Geodorum attenuatum Griff. (Orchidaceae)

Geodorum attenuatum has been found in Thailand, China, India and Vietnam, however, thephytochemical composition and antimicrobial activity of G. attenuatum have not been studiedyet. In this study, the phytochemical composition of ethanol extract of G. attenuatum tuber wasdetermined using liquid chromatography-mass spectrometry (LC-MS) and evaluated itsantibacterial activity of ethanol extract via disk diffusion test. 9 compounds in ethanol extract ofG. attenuatum tuber were identified, such as disaccharide, oxoheneicosanoic acid, shikimic acid,chlorogenic acid, 1-Oleoyl-2-acetyl-glycerol, azafrin, 5,6,7-trihydroxyfavone, 2,3-isopropylidene-1-oleoyl-glycerol and trans-docosanoyl ferulate. Moreover, it’s been proved thatthe ethanol extract of G. attenuatum tuber could inhibit the growth of B. cereus, E. coli, P.aeruginosa, S. enteritidis, S. typhimurium, and S. aureus.

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