Investigation of antimicrobial effects against some microorganisms of aloe vera and nerium oleander also examination of the effects of the xanthine oxidase avtivity in liver tissue treated with cyclosporin

Bu çalışmada aloevera ve nerium oleander bitkilerinin alkol, su ve kloroform fazlarına alman ürünlerinin 8 farklı bakteri ve 2 maya olmak üzere 10 mikroorganizmaya karşı antimikrobiyal aktiviteleri araştırıldı. Aloe vera'nın nerium oleandere göre daha fazla antimikrobiyal aktivite gösterdiği görüldü. Kontrol ve siklosporinli karaciğer dokularındaki ksantin oksidaz enzim aktivitesi araştırıldı ve aloe vera ile nerium oleander'in bu enzim aktivitesine etkisi incelendi. Kontrol karaciğer dokusundaki ksantin oksidaz enzim akti vitesini aloe veranın azalttığı, nerium oleanderin ise az oranda artırdığı gözlendi. Siklosporinin karaciğer dokusundaki ksantin oksidaz enzim aktivitesini inhibe ettiği ve aloe vera ile nerium oleander'in bu inhibisyonu kaldıramadığı görüldü.

Aloe vera ve nerium oleander' in bazı mikroorganizmalara karşı antimikrobiyal aktivitelerinin araştırılması ve bu bitkilerin siklosporinli karaciğer dokusundaki ksantin oksidaz enzim aktivitesine etkilerinin incelenmesi

In this study, the antimicrobial effect of water, alcohol, choloroform extracts of aloe vera and nerium oleander were investigated on ten different strains of bacteria and yeast. Aloe vera has an antimicrobial effect more than nerium oleander. Xanthine oxidase activity of both control tissue and liver tissue treated with cyclosporin and then, the effect of aloe vera and nerium oleander on this enzyme activity were investigated. Xanthine oxidase activity in control liver tissue was decreased, by aloe vera whereas nerium oleander was slightly increased it. It was shown that xanthine oxidase activity in liver tissue was inhibited by cyclosporine but, the inhibition was not prevented by aloe vera and nerium oleander.

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