Burcu TUNCER BALOŞ, Nurdan ÖZMERİÇ, Duygu BOYNUEĞRİ, İmge ERGÜDER, İdil KARAKAYA BAVBEK, Burcu ÖZDEMİR ÇAKILCI, Latife Arzu ARAL, Ayşegül YÜCEL ATAK

Opg-rankl levels after continuous orthodontic force

Amaç: Devamlı ortodontik kuvvet sonrasında hareket ettirilen dişlerin gerilim (mezial) ve basınç (distal) bölgelerinde osteoprotegerin (OPG) ve reseptör aktivatör nüklear faktör kappa-β ligand (RANKL) seviyelerinin değerlendirilmesidir. Yöntemler: Farklı molar ilişkiye sahip, çekimli ortodontik tedavi gereksinimi bulunan ve ortalama yaşları 17.5-18.9 yıl olan dokuz bireye ait (5 kız, 4 erkek) toplam 18 kanin dişi araştırmaya dahil edilmiştir. Birinci küçük azı dişlerinin çekimini takiben üst kanin dişleri braketlenmiş ve 200 gr devamlı kuvvet uygulayan sentaloy kapalı yaylar ile distalizasyon kuvveti uygulanmıştır. Diş eti oluğu sıvısı örnekleri, kanin dişlerin mezial ve distal yüzeylerinden kuvvet öncesi, kuvvetten 1 saat, 24 saat, 168 saat ve 1 ay sonra toplanmıştır. OPG ve RANKL seviyeleri ELISA testi ile analiz edilmiştir. Bulgular: OPG konsantrasyonu kuvvet uygulandıktan 1 saat sonra mezial yüzeyde artarken, distal yüzeyde azalmış olup, bu bulgu istatistiksel olarak anlamlı bulunmuştur (p

Devamlı ortodontik kuvvet sonrası opg-rankl seviyeleri

Objective: To evaluate the levels of osteoprotegerin (OPG) and receptoractivator of nuclear factor kappa-β ligand (RANKL) in tension (mesial) andpressure (distal) sides during continuous orthodontic force.Methods: Eighteen canine teeth of 9 adults (5 female, 4 male; age range17.5-18.9 yrs) with different Angle classifications were included. After firstpremolar extractions, the maxillary canines were tipped distally bysentalloy closed coil springs with a continuous force of 200 g. Gingivalcrevicular fluid (GCF) was sampled from mesial and distal gingival crevicesof each canine separately at baseline, 1 hour(h), 24 h, 168 h, and 1 monthafter force application. OPG and RANKL levels were analyzed by ELISA.Results: Concentration of OPG showed an increase in mesial side, whilethere was a decrease in distal side at 1 h, demonstrating a statisticallysignificant difference (p

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