Hikmet Gülşah TANYILDIZ, Gürses ŞAHİN, Şule TOPRAK, Duygu DÜZCAN KİLİMCİ, Burçak BİLGİN, Şule YEŞİL

Konjenital Hemanjiomların Özellikleri

Hemanjiomlar çocukluk çağının en sık görülen benign tümörleridir. Bilinenrisk faktörleri kız cinsiyet, prematürite ve düşük doğum ağırlığıdır. Buçalışmada bu faktörlere ek olarak hemanjiom gelişimini etkileyebilecekprenatal ve natal risk faktörlerinin araştırılması planlandı. Çalışmaya 114konjenital hemanjiomlu hasta ve 100 sağlıklı çocuk dahil edildi. İki grubunyaş, cinsiyet, prenatal özellikleri (annenin gebelikte ilaç kullanımı, gebeliktegeçirdiği hastalıklar, annede gebelikte hipo-hipertansiyon ve hiperemezisvarlığı, anne ve babanın sigara kullanımı), natal özellikleri (doğum şekli,doğum ağırlığı, gestasyon yaşı), anne-baba yaşı, anne-baba hastalıkları vekullandığı ilaçlar sorgulandı. Konjenital hemanjiomların en sık yerleşim yeribaş-boyun bölgesi idi. Kız olmak ve birinci çocuk olmak konjenital hemanjiomgelişim riskini artırıyordu. Annenin gebeliğinde hiperemezis öyküsününolması konjenital hemanjiom gelişim riskini 1.75 kat artırıyordu. Postterm ve4000 gramın üzerinde doğum konjenital hemanjiom gelişimine karşıkoruyucu idi. Bilinen risk faktörlerinin dışında gebelikte ilaç kullanımının dakonjenital hemanjiom gelişimi için bir risk faktörü olabileceği tespit edildi.İleride konuyla ilgili yapılacak çalışmaların daha geniş hasta gruplarındayapılmasını ve daha farklı risk faktörlerinin de göz önünde bulundurulmasınıöneriyoruz.

Features of Congenital Hemangiomas

Hemangiomas are the most common benign tumors of childhood. The known risk factors are female gender, prematurity, and low birth weight. In this study, it is planned to investigate prenatal and natal risk factors which may affect hemangioma development in addition to these factors. The study included 114 patients with congenital hemangioma and 100 healthy children as the control group. Age, sex, prenatal characteristics of two groups (use of drugs, diseases, hypo-hypertension and hyperemesis during pregnancy, parental smoking), natal features (type of birth, birth weight, gestation age), parents’ age, parents' diseases and medications used were questioned. The most frequent site of congenital hemangiomas was the head and neck region in our study. Female gender and being the first child increased the risk of developing congenital hemangioma. As an important information, hyperemesis during pregnancy increased the risk of congenital hemangioma 1.75 times. Postterm birth and birth weight over 4000 gram were protective against congenital hemangioma development. Apart from the known risk factors, drug use in pregnancy could be a risk factor for the development of congenital hemangioma. We recommend that future studies should be conducted in larger patient groups in order to consider different risk factors.

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