Birol Mehmet UĞUR, Sündüs GENCAY, Ahmet KÖYBAŞIOĞLU, Erdoğan İNAL, Metin YILMAZ, Fikret İLERİ

Epidermoid cancer of the oral cavity: A retrospective analysis

Amaç: Oral kavite epidermoid kanserli hastalarımıza ait TNM klasifikasyonu, evre, cerrahi patoloji, lokorejyonel nüks ve sagkalı oranlan sonuçlarını sunmak. Gereç ve Yöntem Cerrahi veya cerrahi ve sonrasında radyoterapi ile tedavi edilmiş ve üç yıl süreyle takip edilmiş 34 hastanın tıbbi kayıtları incelendi. Hastaların evre dağılımına göre sayı ve yüzdeleri şöyleydi: Evre I: 5 (%14.7), Evre II: 6 (%17.6), Evre 111:14 (%41.1), Evre IV: 9 (%26.7). Sonuçlar: Serinin toplam 3 yıllık sagkalı oranı %67.6 olarak bulundu. Primer tümörün boyutuna göre 3 yıllık sagkalı oranları Tl tümörler için %83.3, T2 için %73.3, T3 için %55.5, T4 için 50.0% olarak saptandı. NO, Nl ve N2 hastalar için 3 yıllık sagkalı sırayla %80, %72.7 ve %37.5 bulundu. Evreye göre sagkalı ise Evre I tümörler için %80, Evre II için %83.3, Evre III için %71.4, Evre W için %44.4 idi. 6hastada lokal nüks (%17.6), 5 hastada (%14.7) refyonel nüks görüldü, Hem lokal hem rejyonel nüks l hastada (2.9%) vardı. Lokal ve rejyonel nüks için 3 yıllık sagkalı sırasıyla %33.3 ve %40 olarak bulundu. Tümörün boyun lenfnodu tutulumunun artmasıyla istatiksel olarak önemli derecede sağkalınin düştüğü gözlendi. Sonuç: intraoral skuamöz kanserlere boyun metastazı olmadan önce tam konması daha iyi tedavi sonuçları için kritik önem taşımaktadır. Boyun metastazı oluştuğunda sagkalı belirgin derecede düşmektedir.

Oral kavite epidermoid kanserleri: Bir retrospektif analiz

Purpose: To present our results with respect to TNM classification, stage, surgical pathology, locoregional recurrence and survival rate of patients with epidermoid cancer of the oral cavity. Methods: The medical records of34 patients treated with surgery alone or surgery -with postoperative radiotherapy and followed up for at least 3 years are reviewed. Number and percentage of the patients according to the stage were as follows: Stage I: 5 (14.7%), Stage 11:6 (17.6%), Stage 111:14 (41.1%), Stage IV: 9 (26.7%). Results: The 3-year survival rate for the complete series was 67.6%. 3-year survival rates with respect to the size of the primary tumor were 83.3% for Tl, 73.3% for T2, 55.5% for T3, and 50.0% for T4 tumors. Survival rates for NO, Nl and N2 patients were 80%, 72.7% and 37.5% respectively. 3-year survival rates according to the stage of the patients were 80% for Stage I, 83.3% for Stage II, 71.4% for Stage III, and 44.4% for Stage IV patients. Local relapse occurred in 6 patients (17.6%), nodal recurrence in 5 patients (14.7%) and both in 1 patient (2.9%). The 3-year survival rate for local relapse and nodal recurrence were 33.3% and 40% respectively. There was a statistically important decrease in the survival rate with advanced lymph node involvement of the tumor. Conclusion: Diagnosis of intraoral cancers before any neck metastasis occurs is of critical importance for improved outcomes. Survival rates get worse in cases with neck metastasis.

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