LOKAL OTOJEN OSTEOKONDRAL GREFT UYGULAMALARI: KÖPEKLERDE DİZ EKLEMİNDE DENEYSEL ÇALIŞMA

Yapılan bu çalışmanın amacı köpeklerde diz eklemindeki osteokondral defektlerin onarımında lokal otojen osteokondral greftlerin uygulanabilirliğini araştırmaktı. Çalışmada 18 adet sağlıklı, yetişkin melez köpek kullanıldı. Osteokondral defektler, standart silindir biçimin-de (0.5 cm x 0.5 cm) femurun lateral ve medial kondyluslarının her ikisinde de oluşturuldu. Oluşturulan defektler 9 köpekte (tedavi grubu) femoral trochlea’nın lateral ve medial kısımlarının üst yüzeylerinden elde edilen otojen osteokondral greftlerle dolduruldu. Dokuz köpek ise kontrol grubu olarak tutuldular. Klinik ve radyolojik kontroller 15 gün aralıklarla gerçekleştirildi. Histopatolojik kontroller ise 15, 30 ve 60. günlerde gerçekleştirildi. Sonuç olarak, bulgular köpeklerin diz eklemindeki osteokondral defektlerin, lateral ve medial femoral trochlea’nın üst kısımlarından elde edilen otojen osteokondral greftlerle sağaltımlarının gerçekleştirilebilece-ğini göstermiştir.

Anahtar Kelimeler:

Otojen Osteokondral Greft, Köpek

LOCAL AUTOGENOUS OSTEOCHONDRAL GRAFT APPLICATIONS: AN EXPERIMENTAL STUDY IN DOGS KNEE JOINTS

The aim of this study was to investigate applicability of local autogenous osteochondral grafts for the repairment of osteochondral defects in knee joints of dogs. The material consisted of 18 healthy adult mongrel dogs. Osteochondral defects in standard cylindrical shape (0.5 cm x 0.5 cm) were created on both lateral and medial femoral condyles.The defects were filled with autogenous osteochondral grafts harvested from upper surface of lateral and medial labium of femoral trochlea in treatment group (9 dogs). Nine dogs were kept as control group. Clinical and radiographical evaluations were carried out at the 15 days intervals. Histopathological examinations were carried out at the 15th, 30th and 60th days in each group. Consequently, the results indicated that autogenous osteochondral grafts harvested from upper surface of lateral and medial labium of femoral trochlea could be applied in treatment of osteochondral defects in knee joints of dogs.

Keywords:

Autogenous Osteochondral Graft, Dog,

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