Sedanterlerde Gliserol Takviyesinin Plazma Aldosteron Düzeyleri Üzerine Etkisi

Giriş: Bu çalışmanın amacı, sedanterlerde gliserol uygulamasının plazma aldosteron düzeylerini nasıl etkilediğini araştırmaktır. Gereç ve Yöntem: Çalışma yaş ortalamaları 22.82±1.49 yıl ve vücut ağırlığı ortalamaları 73.96±9.16 kg olan ve Selçuk Üniversitesi'nin değişik fakültelerinde okuyan 20 sağlıklı erkek üzerinde gerçekleştirildi. Denekler iki gruba (Sedanter grup (S), Gliserol takviyeli sedanter grup (GS) ayrıldı. Her iki gruptaki deneklere 20. günün sonunda 20 m mekik koşu testi uygulandı. GS grubuna dahil olan deneklere 20 gün boyunca sabah saat 10.00'da oral olarak 1.2 g/kg dozunda gliserol 1.5 lt su ile karıştırılarak takviye yapıldı. Bütün deneklerden egzersiz periyoduna ve gliserol takviyesine başlamadan önce kan örnekleri alındı. Ayrıca, 20 günlük gliserol takviyesinden sonra tüm deneklerden ikinci kan örnekleri alındı. 20. günün sonunda her iki gruba da belirtilen egzersiz testi uygulandı. Egzersiz testinin bitiminden hemen sonra üçüncü kan örnekleri alındı. Egzersizden 2 saat sonra dördüncü ve 24 saat sonra besinci kan örnekleri alındı. Alınan kan örneklerinde belirlenen plazma aldosteron düzeyleri ölçüldü.. Bulgular: Her iki grubun aldosteron düzeyleri yapılan 5 ölçümde de birbirinden farklı değildi. Egzersizden hemen sonra hem GS, hem de S grubunun plazma aldosteron düzeyleri egzersiz öncesi değerlerden önemli şekilde yüksekti (p
Anahtar Kelimeler:

Gliserol, Aldosteron, Egzersiz

The Effects of Glycerol Supplement on Plasma Aldosterone Levels in Sedentaries

Objectives: The aim of this study is to search the effects of the glycerol supplement on the levels of plasma aldosteron of sedentaries. Material and Method: In this study, 20 students with an average age of 22.82 ± 1.49 year and an average weight of 73.96 ± 9.16 kg, who attend currently at the other faculties of Selçuk University, were used as subjects. Subjects were divided into two groups which were sedentaries (S) and sedentaries supplemented with glycerol (GS). The test of shuttle and run of 20 meters was applied to subjects in the groups S and GS at the end of 20th days. Subjects of the group GS were supplemented orally 1,5 lt water with the dose of 1.2 g/kg of glycerol at ten o'clock every morning during the period of twenty days. At the same time, samples of blood were taken from all the subjects before tests and supplemented with glycerol. Besides, samples of blood were taken from subjects only in the group GS after the supplemented with glycerol. At the end of 20th days, the specified exercise tests were applied to two groups after the second blood test. Just after the exercise tests, samples of blood were taken from the subjects the third time. Then, the samples of blood were taken from them two hours later after the exercises the fourth time and also twenty four hours later after the same exercises the fifth time again. Results: The level of plasma aldosteron of blood samples of all groups was almost similar in 5 measured. The level of plasma aldosteron of blood samples of all groups just after exercise was higher significantly than that before exercise (p
Keywords:

-,

___

  • Fallo F. Renin-angiotensin-aldosterone system and physical exercise.J Sports Med Phys Fitness, 1993; 33: 306-312. 2. Robergs RA, Griffin SE. pharmacokinetics andclinical and practical applications. Sports Med, 1998; 3: 145-167. Glycerol. Biochemistry,
  • Freund BJ, Montain SJ, Young AJ, et al. Glycerol hyperhydration: hormonal, renal, and vascular fluid responses. J Appl Physiol 1995; 79: 2069-2077.
  • Goulet E. Effect of Glycerol Hyperhidration Before Exercise in Trained Triathlets on Endurance Performance and Cardiovascular and Thermoregulatory Responses. 2001.
  • Coutts A, Reaburn P, Mummery K, Holmes M. The effect of glycerol performance in high ambient temperatures. Int J Sport Nutr Exerc Metab 2002; 12: 1: 105-119. olympic distance triathlon
  • Murray R, Eddy DE, Paul GL, Seifert JG, Halaby GA. Physiological responses to glycerol ingestion during exercise. Am Physiological Soc 1991; 1: 144-149.
  • Goulet E, Gauthier P, Labrecque S, Royer D. Glycerol hyperhydration, endurance performance and cardiovascular and thermoregulatory responses: a case study of a highly trained triathlete. Journal of Exercise Physiology, 2002; 5.
  • Marino FE, Kay D, Cannon J. Glycerol hyperhydration fails to improve endurance performance and thermoregulation in humans in a warm humid environment. Pflugers Arch. 2003; 446: 455- 462.
  • Montner P, Stark DM, Riedesel ML, et al. Pre-exercise glycerol hydration improves cycling endurancetime. Int J Sports Med 1996; 17: 27-33.
  • Anderson MJ, Cotter JD, Garnham AP, Casley DJ, Febbraio MA. Effect of glycerol-induced hyperhydration on thermoregulation and metabolism during exercise in the heat. International Journal of Sport Nutrition and Exercise Metabolism, 2001; 11: 315-333.
  • Hitchins S, Martin DT, Burke L, et al. Glycerol hyperhydration improves cycle time trial performance in hot humid conditions. European Journal of Applied Physiology, 1999; 80: 494-501.
  • Lyons TP, Riedesel ML, Meuli LE, Chick TW. Effects of glycerol-induced hyperhydration prior to exercise in the heat on sweating and core temperature. Med Sci Sports Exerc 1990; 22: 477-483.
  • Tamer K. Sporda Fiziksel-Fizyolojik Performansın Ölçülmesi ve Değerlendirilmesi Bağırgan Yayımevi, Kültür Matb 2000, Ankara.
  • Özdamar K. Paket Programları ile İstatiksel Veri Analizi. Anadolu Ünv Yayınları, No.1001, 1997, Eskişehir.
  • Rietjens GJ, Kuipers H, Hartgens F, Keizer HA. Red blood cell profile of elite olympic distance triathletes. A thre-year follow- up. Int J Sports Med 2002; 23: 391-396.
  • Kinugawa T, Ogino K, Miyakoda H, et al. Responses of Catecholamines, Natriuretic Peptide to Exercise in Untrained Men and Women. Gen Pharmac 1997; 28: 2: 225-228. System, and Atrial
  • Mannix ET, Plange P, Aronof GR, Manfredi F, Farber MO. Atrial natriuretic peptide and the renin-aldosteron axis during exercise in man. Med Sci Sports Exerc 1990; 22: 6, 785-789.
  • Noyan A. Yaşamda ve Hekimlikte Fizyoloji. 12. Baskı, Meteksan An. Şir, 2000, Ankara.
  • Pastene J, Germain M, Allevard AM, Gharib C, Lacour JR. Water balance during and after marathon running. Eur J Appl Physiol Occup Physiol 1996; 73: 49-55.
  • Yılmaz B. Hormonlar ve Üreme Fizyolojisi. Feryal Matbaa, 1.Basım, 1999; 247-371, Ankara.
  • Kavouras SA, Armstrong LE, Maresh CM, et al. Rehydration with glycerol: endocrine, cardiovascular and thermoregulatory responses during exercise in the heat. J Appl Physiol 2006; 100: 442-450.
  • Maresh CM, Gabaree-Boulant CL, Armstrong LE, et al. Effect of hydration on thirst, drinking and related hormonal responses during low-intensity exercise in the heat. J Appl Physiol 2004; 97: 39-44.
  • Melin B, Jimenez C, Savourey G, et al. Effects of hydration state on hormonal and renal responses during moderate exercise in the heat. Eur J Appl Physiol, 1997; 76: 320-327.
  • Podhorska OM, Dziegel P, Gomulkiewez A, et al. The role of AT1 and AT2 angiotensin receptors in the mechanism of apoptosis in renal tubular cells after physical exercise. Rocz Akad Med Bialymst 2004; 49: 8-10.
  • Bocqueraz O, Koulmann N, Guıgas B, Jımenez C, Melın B. Fluid-Regulatory Hormone Responses during Cycling Exercise in Acute Hypobaric Hypoxia. Medicine Science in Sports Exercise 2004; 36: 10: 1730-1736.
  • Freund BJ, Shızuru EM, Hashıro GM, Claybaugh JR. Hormonal, electrolyte and renal responses to exercise are intensity dependent. J Appl Physiol 1991; 70: 900-906.
  • Melin B, Eclache JP, Geelen G, at al. Plasma AVP, Neurophysin, Renin Activity and Aldosterone During Submaximal Exercise Performed Until Exhaustion in Trained and Untrained Man. Eur J Appl Physiol 1980; 44; 141-151.
  • Morgan RM, Patterson MJ, Nimmo A. Acute effects of dehydration on sweat composition in men during prolonged exercise in the heat. The American College of Sports Medicine 2004; 182: 37.
  • Milledge JS, Bryson EI, Catlev DM, at al. Sodium Balance, Fluid hHomeostasis and The Renin Aldosterone System During The Prolonged Exercise of Hill Walking. Cli Sci 1982; 62: 595-604.
  • Williams ES, Ward MP, Milledge JS, Withey WR, Older MWJ, Forsling ML. Effect of The Exıercise of Seven Consecutive Days Hill-Walking on Fluid Homeostasis. Cli Sci 1979; 56: 305-316.
  • Guyton MD, Hall JE. Textbook of Medical Physiologh. Tıbbi Fizyoloji (Çev: Çavuşoğlu H), 9. Baskı, Yüce Yayınları, 1996, İstanbul.
  • Günay M, Cicioğlu İ. Spor Fizyolojisi. Gazi Kitabevi, Baran ofset, 1.baskı, 2001, Ankara.
  • Aurell M, Vikgren P. Plasma Renin Activity in Suıpine Muscolar Exercise. J App Physiol 1971; 31: 839-841.
  • Kozlowski S, Brzezinska Z, Nazar K, Kowalski W, Franczyk M. Plasma Catecholamines During Sustained İsometric Exercise. Clin Sci Mol Med 1973; 15: 723-731.
  • Kabul Tarihi: 29.05.2007
Fırat Tıp Dergisi-Cover
  • ISSN: 1300-9818
  • Başlangıç: 2015
  • Yayıncı: Fırat Üniversitesi Tıp Fakültesi
Sayıdaki Diğer Makaleler

Saçma Yaralanmasına Bağlı Akut Miyokard Enfarktüsü ve EKG

Seda ÖZKAN, Okhan AKDUR, Polat DURUKAN, İbrahim İKİZCELİ, Levent AVŞAROĞULLARI, Murat YÜCEL, Erdoğan Mütevelli SÖZÜER

NOS İnhibisyonu Aracılı Hipertansiyon: Sıçanlarda Sabit ve Kademeli doz L-NNA Uygulamalarının Karşılaştırılması

Süleyman OKTAR, Engin YILMAZ, Engin ŞAHNA, Hakkı Engin AKSULU

Formaldehit Nörotoksisitesine Bağlı Hipokampusta Gelişen Oksidatif Hasar ve Melatonin Hormonunun Koruyucu Etkisi: Deneysel Bir Çalışma

İlter KUŞ, İsmail ZARARSIZ, Murat ÖGETÜRK, H. Ramazan YILMAZ

Sedanterlerde Gliserol Takviyesinin Plazma Aldosteron Düzeyleri Üzerine Etkisi

Süleyman PATLAR, Ercan KESKİN, Oktay ÇAKMAKÇI

Pediküler Kemik Defektinin Eşlik Ettiği Asemptomatik Adult Diastematomyelia: BT ve MRG Bulguları

Ahmet KAVAKLI, Hanefi YILDIRIM, Murat ÖGETÜRK, İlter KUŞ, Evren KÖSE, Mustafa SARSILMAZ

Hipohidrotik Ektodermal Displazi Tanılı Dört Olgu Sunumu: Christ-Siemens-Touraine Sendromu

Saadet AKARSU, Özlem ELKIRAN, İsmail ŞENGÜL, Ceren KARA, Başak Kandi COŞKUN, Bengü ÇOBANOĞLU

Tiroglossal Duktus Kist ve Fistülleri: 32 Vakalık Bir İnceleme

Hayrettin Cengiz ALPAY, İrfan KAYGUSUZ, Turgut KARLIDAĞ, Erol KELEŞ, Şinasi YALÇIN, Hakan DABAK

Dijital Görüntü İşleme Teknikleri Kullanılarak Sperm Sayımında Yeni Bir Yaklaşım

İsmail BABAOĞLU, Ferruh YILDIZ, Metin ÇAPAR, Lütfiye ALP

İnfantil Dönemde Bir Herpes Zoster Olgusu

Demet ÇİÇEK

Akciğer Metastazlı, Kemiğin Dev Hücreli Tümörü: Kemoterapi ve Tüm Akciğer Radyoterapi Tedavi Kombinasyonu. Olgu Sunumu

Cenk ÖZKAN, Aydıner KALACI, Serdar ÖZBARLAS