Alp SARUHANOĞLU, Nazlı ALTIN, Sertan ERGUN, Hakkı TANYERİ

ORAL LÖKOPLAKİNİN MALİGN TRANSFORMASYONU: OLGU SUNUMU-Malign Transformation of Oral Leukoplakia: A Case Report

ÖZOral lökoplaki, oral mukozada en sık görülen premalign lezyon olup klinik ya da patolojik olarak herhangi bir hastalığa ait olmayan beyaz-gri plaklar ile karakterizedir. Lökoplakinin de dahil olduğu premalign lezyonlar, biyolojik davranışı selim olan ancak histopatolojik olarak hücrelerde atipi kriterleri ve maligniteye dönüşme potansiyeli taşıyan lezyonlardır. Premalign lezyonların başlangıcından itibaren düşük dereceli maligniteler olarak değerlendirilerek belirli aralıklarla takip edilmeleri önerilmektedir. Bu olguda oral lökoplaki tanısıyla takip edilen hastada lökoplakinin malign transformasyon ile oral skuamoz hücreli karsinom gelişimi göstermesi rapor edilmiştir.Anahtar kelimeler: Lökoplaki, malign transformasyon, oral kanserABSTRACTLeukoplakia considered as the most common premalignant oral lesion of the oral cavity and defined as, "a white patch or plaque that cannot be characterized clinically as any other disease". Precancerous lesions including oral leukoplakia have a benign biological, but the histopathological examination demonstrates atypical cells confined to the epidermis. These lesions have carcinogenic potential. Patients should be followed up in terms of malignancy risk. In this case transformation of leukoplakia into oral squamous cell carcinoma is reported.Keywords: Leukoplakia, malign transformation, oral cancer

Anahtar Kelimeler:

Lökoplaki, malign transformasyon, oral kanser

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Leukoplakia considered as the most common premalignant oral lesion of the oral cavity and defined as, “a white patch or plaque that cannot be characterized clinically as any other disease”. Precancerous lesions including oral leukoplakia have a benign biological, but the histopathological examination demonstrates atypical cells confined to the epidermis. These lesions have carcinogenic potential. Patients should be followed up in terms of malignancy risk. In this case transformation of leukoplakia into oral squamous cell carcinoma is reported.

Keywords:

Leukoplakia, malign transformation, oral cancer,

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