Kronik obstrüktif akciğer hastalığı alevlenmesi ve sonuçları

Kronik obstrüktif akciğer hastalığının alevlenme periyodu, stabil dönemdeki hastalık bulgularından farklı olarak akut gelişen yakınmalarla karakterizedir. Bu dönemde hastaların en önemli yakınmaları, akut veya subakut bir zaman diliminde artan nefes darlığı, öksürük, balgam miktarı ve balgam pürülansıdır. Bu makalede KOAH alevlenmesinde yer alan etyolojik faktörler ve alevlenmenin hasta ve toplum sağlığı üzerine olan etkileri tartışılacaktır.,

Anahtar Kelimeler:

KOAH, Alevlenme, Etyoloji, Toplumsal Maliyet

Exacerbations of chronic obstructive pulmonary disease and it's results

The exacerbation period of chronic obstructive pulmonary disease (COPD) is differentiated with rapidly developing symptoms from the stable period. The most important complaints of the patients in this period are; progressive dispne, cough, increase in sputum quantity and purulance. In this paper we will discuss the etiologic factors of exacerbations of COPD and the impact on the patient's and community health.

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l.Chojnowski D. "GOLD" standards for acute exacerbation in COPD. Nurse Pract. 2003;28:26-35
2.Hurst JR, Wedzicha JA. Chronic obstructive pulmonary disease: the clinical management of an acute exacerbation. Postgrad MedJ. 2004;80:497-505
3.Quon BS, Gan WQ, Sin DD. Contemporary management of acute exacerbations of COPD: a systematic review and metaanalysis. Chest. 2008;133:756-66
4.Sapey E, Stockley RA. COPD exacerbations. 2: aetiology. Thorax. 2006;61:250-8
5.Aaron SD, Fergusson D, Marks GB, Suissa S, Vandemheen KL, Doucette S, et al. Counting, analysing and reporting exacerbations of COPD in randomised controlled trials. Thorax. 2008;63:122-8
6.Wedzicha JA, Donaldson GC. Exacerbations of chronic obstructive pulmonary disease. Respir Care. 2003;48:1204-15
7.Anzueto A, Sethi S, Martinez FJ. Exacerbations of chronic obstructive pulmonary disease. Proc Am Thorac Soc. 2007;4:554-64
8.Llor C, Molina J, Naberan K, Cots JM, Ros F, Miravitlles M; EVOCA study group. Exacerbations worsen the quality of life of chronic obstructive pulmonary disease patients in primary healthcare. Int J Clin Pract. 2008;62:585-92
9.Quint JK, Baghai-Ravary R, Donaldson GC, Wedzicha JA. Relationship between depression and exacerbations in COPD. Eur Respir J. 2008;32:53-60
lO.O'ReillyJF, Williams AE, Holt K, Rice L Defining COPD exacerbations: impact on estimation of incidence and burden in primary care. Prim Care Respir J. 2006;15:346-53
ll.Burge S, Wedzicha JA. COPD exacerbations: definitions and classifications. Eur Respir J Suppl. 2003;41:46-53
12.McGhan R, Radcliff T, Fish R, Sutherland ER, Welsh C, Make B. Predictors of rehospitalization and death after a severe exacerbation of COPD. Chest. 2007; 132:1748-55
13.Garcia-Aymerich J, Farrero E, Felez MA, Izquierdo J, Marrades RM, Antö JM; Estudi del Factors de Rise d'Aguditzaciö de la MPOC investigators. Risk factors of readmission to hospital for a COPD exacerbation: a prospective study. Thorax. 2003;58:100-5
14.Soler-Cataluna JJ, Martinez-Garcia MA, Roman Sanchez P, Salcedo E, Navarro M, Ochando R. Severe acute exacerbations and mortality in patients with chronic obstructive pulmonary disease. Thorax. 2005;60:925-31
15.Wouters EF. Local and systemic inflammation in chronic obstructive pulmonary disease. Proc Am Thorac Soc. 2005;2:26-33
16.Miravitlless M. Exacerbations of chronic obstructive pulmonary disease: when are bacteria important? Eur Respir J Suppl. 2002;20:9-19
17.Taşbakan MS, Sayıner AA, Sayıner A. KOAH infektif alevlenmelerinde atipik patojenlerin rolü/Tüberküloz ve Toraks Dergisi, 2007;55:336-41
18.Brunton S, Carmichael BP, ColganR, Feeney AS, Fendrick AM, Quintiliani R, et al. Acute exacerbation of chronic bronchitis: a primary care consensus guideline. Am J Manag Care. 2004; 10:689-96
19.Wedzicha JA. Role of viruses in exacerbations of chronic obstructive pulmonary disease. Proc Am Thorac Soc. 2004; 1:115-20
2O.Taşbakan MS, Sayıner AA, Sayıner A. KOAH infektif alevlenmelerinde atipik patojenlerin rolü. Tüberküloz ve Toraks Dergisi, 2007;55:336-41
21.Brunton S, Carmichael BP, ColganR, Feeney AS, Fendrick AM, Quintiliani R, et al. Acute exacerbation of chronic bronchitis: a primary care consensus guideline. Am J Manag Care. 2004; 10:689-96
22.Calverley PM. Reducing the frequency and severity of exacerbations of chronic obstructive pulmonary disease. Proc Am Thorac Soc. 2004; 1:121-4
23.Burge PS. Prevention of exacerbations: how are we doing and can we do better? Proc Am Thorac Soc. 2006;3:257-61
24.Seemungal T, Wedzicha JA. Acute exacerbations of chronic obstructive pulmonary disease:treatment and prevention. Medicine. 2008;36:223-5
25.Puhan MA, Scharplatz M, Troosters T, Steurer J. Respiratory rehabilitation after acute exacerbation of COPD may reduce risk for readmission and mortality -a systematic review. Respir Res. 2005;8:54
26.Elci A, Borekci S, Ovayolu N, Elbek O. The efficacy and applicability of pulmonary rehabilitation programme for patients with COPD in a secondary-care community hospital. Respirology. 2008; 13:703-707