Osman BAŞPINAR, Metin KILINÇ, Erkan ALTUNCU, Mesut PARLAK, Yavuz COŞKUN

Prognostic effect of conventional treatment in pediatric dilated cardiomyopathy

Pediatrik dilate kardiyomiyopatili hastalarımızda konvensiyonel tedavide prognoza etki eden faktörleri araştırmayı planladık. Son altı yıl içinde hastanemizde tedavi edilen 41 dilate kardiyomiyopatili çocuk hastanın retrospektif değerlendirmesi yapıldı. 23 kız, 18 erkek, başlangıç ejeksiyon fraksiyonu ortalama %31.6±7.8, izlem süresi ise 14.0±14.2 ay idi. İzlemde 8 hasta (%19.5) öldü, 17 hastanın (%41.4) sistolik fonksiyonu zamanla düzeldi. Sistolik fonksiyonu düzelen hastaların başlangıç ejeksiyon fraksiyon değerleri düzelmeyenlere göre istatistiksel olarak anlamlı değildi (p=0.743). Başvuru yaşlarına göre hastalar iki gruba ayrıldığında %58.5 hasta iki yaştan küçüktü. İki yaştan küçük hastalardan altısı (%25), iki yaştan büyüklerden ise ikisi (%11.7) öldü. Grupların karşılaştırılması istatistiksel olarak anlamlı bir fark vermedi (p=0.632). Hastalığın başlangıç yaşı ve sistolik fonksiyonun başlangıç değerinin hastalık prognozunu göstermede etkin olmadığını düşünmekteyiz.

Anahtar Kelimeler:

Dilate kardiyomiyopati, Prognoz, Çocukluk çaðý

Pediatrik dilate kardiyomiyopatide medikal tedavinin prognoza etkisi

The purpose of this study was to review our experience with conventional treated pediatric dilated caridomyopathy patients in our region and attempt to discover prognostic factors. We analyzed retrospectively the outcome of 41 patients during last six years. The patients were 23 girls, and 18 boys, ejection fraction 31.6±7.8%, follow-up period 14.07Ü4.2 months. Eight patients (19.5%) had died, 17 (41.4%) had recovery of systolic function. When analyzed from regained normal systolic function, first ejection fraction was not statistically significant (p=0.743). When separated from patient presentation age, 58.5% were smaller than two years. Sixth patients (25%) were died in smaller and two (11.7%) in bigger. Comparison between groups were not statistically differences (p=0.632). We concluded that age; degrees of systolic functions were not differentiated favorable outcomes.

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