Increased thrombolysis in myocardial infarction frame counts in patients with chronic aortic regurgitation

Amaç: Kronik aort yetersizliği (AY) koroner kan akımının sistolik/diastolik fazı ve koroner akım rezervini etkilemektedir. Thrombolysis in myocardial infarction (TIMI) kare sayı koroner kan akımı ile korele olup, yüksek TIMI kare sayısı (TKS) prekapiller arteriyol damar fonksiyon bozukluğunu ğöstermesine rağmen AY’e hastalarında araştırılmamıştır. Metod: Çalışmaya ekokardiyografi ve anjiografi ile tanı konulan 33 izole kronik aort yetersizliği hastası ile atipik ğöğüs ağrısı nedeniyle koroner anjiogarfi yapılıp koroner ve valvüler hastalığı olmayan 22 kontrol grubu dahil edilmiştir. Koroner kan akımı TKS ile değerlendirilmiştir. İki grubun koroner kan akımı, ekokardiyografi ve demoğrafik parametreleri karşılaştırılmıştır. Bulgular: Aort yetersizliği hastalarında ortalama TKS’e kontrol grubuna göre daha yüksek olarak saptanmıştır. Düzeltilmiş LAD TKS, 25.0±4.3 vs. 17.6 ± 3.5 kare/s, p

Kronik aort yetersizliği hastalarında artmış thrombolysis in myokardial infarktüs kare sayısı

Aim: The effects of chronic aortic regurgitation (AR) on coronary blood flow of systolic/diastolic phase and phase and coronary reserve have been shown. Whereas thrombolysis in myocardial infarction (TIMI) frame count, which incorporates coronary blood flow and a higher TIMI frame count (TFC) is reflect disordered resistance vessel function, has not yet been evaluated in chronic AR. Method: 33 patients with isolated chronic AR diagnosed by echocardiography and angiography, and 22 control groups with no coronary or valvular disease who underwent angiography for atypical chest pain were included in our study. Coronary blood flow was measured using TFC. Result: Coronary blood flow, echocardiographic and demographic parameters were compared between the two groups. The mean TFC is found to be higher in AR patients when compared to the control group. (left anterior descending coronary artery (LAD) TFC, 43±7.3 vs. 30±5.9 frames/s, p

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