Neutropenic Toxic Epidermal Necrolysis Due to Sulfonamide Use

Yüksek mortalite ve morbidite oranlarına sahip toksik epidermal nekroliz (TEN) genellikle ilaç tedavisinden sonra gelişir. Klinik olarak, mukoza ve cildin en az% 30'u tutulur. Nötropeni TEN olgularında çok nadir görülür ve doğrudan mortalite ile ilişkilidir. Takip sırasında nötropeni gelişen ve erken tanı ve etkili tedavi ile tam iyileşme ile taburcu edilen TEN tanılı bir vakayı paylaşmak istedik.

Anahtar Kelimeler:

Nötropeni, Kotrimaksazol, Toksik epidermal nekroliz

Neutropenic Toxic Epidermal Necrolysis Due to Sulfonamide Use

Toxic Epidermal Necrolysis (TEN), which has high mortality and morbidity rates, often develops after medication. Clinically, at least 30% of the mucous membranes and skin are involved. Neutropenia is very rare in TEN cases and is directly related to mortality. We wanted to share a case diagnosed with TEN, caused by trimethoprim/sulfamethoxazole, who developed neutropenia during follow-up and was discharged with full recovery with early diagnosis and effective treatment.

Keywords:

toxic epidermal necrolysis, neutropenia, cotrimoxazole,

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