Hypervitaminosis A

A Vitamini yaşam için esastır ve ilk bulunan vitamindir. Büyüme, üreme, görme ve bağışıklık sistemi üzerinde birçok etkisi vardır. Son zamanlarda, gıdalarla ve ek ilaçlarla artmış A vitamini alımına bağlı zehirlenmelerle karşılaşılmaktadır. A vitamini eksikliği konusunda birçok çalışma yapılmış bu konuda gelişmiş ve gelişmekte olan ülkelerde yeterli önlemler alınmıştır. Ancak A vitamini zehirlenmesi konusunda yeterli araştırma yapılmaması ve konuyla ilgili gerekli önlemlerin alınmaması nedeniyle gelecekte ortaya çıkacak sağlık risklerini tahmin etmek zordur. Özellikle genç erişkinlerde akut zehirlenme nadiren bildirilmiştir, çünkü A vitamini akut fazda vücut tarafından oldukça tolere edilir. Çoğunlukla yüksek dozda A vitaminine kronik maruz kalmadan sonra gelişen zehirlenme birçok organı etkiler. A vitamini zehirlenmesinin, spesifik tedavisinin yapılmadığında ne kadar ciddi bir halk sağlığı problem haline gelebileceğini anlamak için ileri epidemiyolojik çalışmalara ihtiyaç vardır.

Anahtar Kelimeler:

A vitamini, Retinoik asit, Zehirlenme

Hypervitaminosis A

Since vitamin A is essential for life, it has been added to most of the convenience foods in developed countries. Just as the harmful effects of vitamin A deficiency are known and necessary steps are taken with food and medicine supplements to eliminate this deficiency, so the presence of toxicity, as well as health and well-being, should be monitored in individuals exposed to high doses of vitamin A. Furthermore, the distribution and storage of vitamin A should be examined and genetic studies should be performed to determine individual tolerances in the face of increased hypervitaminosis A problem.

Keywords:

Vitamin A, Toxication, retinoic asid,

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