Hatice Şeyma AKÇA, Abdullah ALGIN, Serdar ÖZDEMİR, Kamil KOKULU, İbrahim ALTUNOK

Evaluation of the Relationship of Serum Digoxin Levels with Demographic Data

Amaç: Digoksin zehirlenmesi ile başvuran hastaların serum digoksin düzeylerini ve demografik verilerinin karşılaştırılması amaçlanmıştır. Gereç ve Yöntem: Bu çalışma retrospektif olarak planlanmıştır. Acil servise şüpheli digoksin zehirlenmesi şikayeti ile başvuran hastalar çalışmaya dahil edildi. Verilerine ulaşılamayan veya 18 yaşından küçük hastalar çalışma dışı bırakıldı. Bulgular: Retrospektif çalışmamızda toplam 118 hasta incelendi. Bunlardan 38’i (% 32,2) erkek, 80’i kadındı (% 67,8). Digoksin seviyesi 2 ng / mL’nin üzerinde olan hastalar zehirlenme açısından değerlendirildi. Digoksin zehirlenmesi 31 hastada (% 26.3) tespit edildi. Digoksin zehirlenmesi olan 31 hastanın 19’u (% 61,2) hastaneye yatırıldı. Digoksin intoksikasyon başvuru şikayeti olan hastalar 6 hastada (% 19,35) yorgunluk, 4 hastada (% 12,9) bulantı, 4 hastada (% 12,9) bradikardi ve 4 hastada (12,9) genel durum bozukluğu mevcuttu. Sonuç: Digoksin zehirlenmesinde kan seviyesi her zaman belirleyici olmayabilir. Şüpheli digoksin zehirlenmesi vakalarında, ayrıntılı bir anamnez, fizik muayene, EKG bulguları rutin elektrolit ve diğer kan testleri incelenmeli ve kardiyoloji kliniğine konsültasyon planlanmalıdır.

Anahtar Kelimeler:

Digoksin zehirlenmesi, digoksin seviyeleri, demografik veriler, acil servis

Evaluation of the Relationship of Serum Digoxin Levels with Demographic Data

Objective: We aimed to compare patients presenting with digoxin intoxication clinic with serum digoxin levels with demographic data. Materials and Methods: This is a retrospective study. Patients admitted to the emergency room with suspected digoxin intoxication included into the study. Patients with missed data, and patients younger than 18 years were excluded. Statistical analysis was performed using the SPSS v25 (SPSS Inc, Chicago, IL) program package. Results: A total of 118 patients were investigated in our retrospective study. Among these, 38 (%32,2) were men and 80 were female (%67,8). Patients with a digoxin level above 2 were evaluated for intoxication. Digoxin intoxication was detected in 31 patients (26.3%). Of 31 patients with digoxin intoxication, 19 (61.2%) were hospitalized. Patients who had digoxin intoxication admission complaints were fatigue in 6 patients (19,35%), nausea in 4 patients (12,9%), bradycardia in 4 patients (12,9%), and general condition disorder in 4 patients (12,9%). Conclusion: Blood level in digoxin intoxication may not always be decisive. After a detailed anamnesis, physical examination, ECG findings should be followed, routine electrolyte and other blood tests should be examined and cardiology should be consulted.

Keywords:

Digoxin intoxication, digoxin levels, demographic data, emergency service,

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