Yavuz ULUSOY, Bahadır KILINÇ, Halil PİR, Funda TERZİ, Orhan DUDAKLI

İneklerde kronik (izole) organ tüberkülozunun patomorfolojik ve immünohistokimyasal değerlendirilmesi

Olguyu patomorfolojik ve immünhistokimyasal olarak ortaya koymayı amaçladık. Bu raporda geç dönemde bir sığırda gelişen kronik, izole organ tüberkülozuna ait genel bulgular sunulmuştur. Vakanın öyküsünde 2 yaşındaki sığır solunum sıkıntısı sonucu ölmüş olup ölüm nedeninin tespiti için patoloji laboratuvarına getirilmiştir. Nekropside, sağ akciğerin kaudal lobunda lokalize kapsüllenmiş kazeöz odaklar ile mediastinal lenf düğümlerinin inaktif olduğu tespit edildi. Histopatolojik olarak mineralize olmayan, sekonder kazeöz nekroz, periferal mononükleer hücre infiltrasyonu ve fibröz kapsül tespit edildi. İmmünohistolojik olarak, bazı makrofajlar ve nötrofillerin Mycobacterium bovis açısından pozitif olduğu görüldü. Ancak bölgesel lenf düğümleri negatifti. Ayrıca, diğer parankimatöz organlarda histopatolojik reaksiyon yoktu. Sonuç olarak, postprimer tüberküloz formu, diğer formlarla karşılaştırıldığında her zaman tespit edilemez. Bu nedenle, bu olgu raporunun yararlı olabileceğine inanıyoruz. Anahtar kelimeler: İnek, kronik organ tüberkülozu, immünolojik tespit, patomorfoloji.

Anahtar Kelimeler:

İnek, kronik organ tüberkülozu, immünolojik tespit, patomorfoloji., İnek, kronik organ tüberkülozu, immünolojik tespit, patomorfoloji.

Pathomorphological and immunohistochemical evaluation of chronic (isolated) organ tuberculosis in a cow

We aimed to reveal the case pathomorphological and immunohistochemically. General findings of chronic isolated organ tuberculosis in cattle in the late period are presented in this report. In the history of the case, the 2-year-old cattle died as a result of respiratory distress and was brought to the pathology laboratory to determine the cause of death. In necropsy, it was detected that encapsulated caseous foci localized in the caudal lobe of the right lung and mediastinal lymph nodes were inactive. Histopathologically, non-mineralized, secondary caseous necrosis, peripheral mononuclear cell infiltration, and fibrous capsule were detected. Immunohistologically, some macrophages and neutrophils were found to be positive for Mycobacterium bovis. However, regional lymph nodes were negative. Also, there was no histopathological reaction in other parenchymatous organs. As a result, the postprimary form of tuberculosis is not always detectable when compared to other forms. Therefore, we believe that this case report may be useful. Keywords: Cow, chronic organ tuberculosis, immunological detection, pathomorphology.

Keywords:

Cow, chronic organ tuberculosis, immunological detection, pathomorphology.,

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