Tiroid kistlerine perkütan etanol enjeksiyonu

Amaç: Benign kistik tiroid nodülü olan ve Doppler ultrasonografi eşliğinde perkütan etanol enjeksiyonu (PEİ) uygulaması ile tedavi edilen 28 hastamızın sonuçları sunuldu. Yöntem: Perkütan etanol enjeksiyonu uygulamasından önce tüm hastalarda ince iğne aspirasyon biyopsisi ile malignite dışlandı. Kist hacmi uzunluk χ yükseklik χ en χ π/6 formülü kullanılarak hesaplandı. Uygulamada başlangıç kist hacminin yarısı kadar %95'lik etil alkol kullanıldı. Hastalarımızın takiplerinde nodül çapı, fibroskleroz oluşumu ve nodül vaskülarizasyonu değerlendirildi. Başlangıç hacmine göre %50'den fazla küçülme başarı olarak kabul edildi. Bulgular: Bir PEİ uygulaması ile hastalarımızın %88.5'inde tedavi edildi. Başarısız olgularda ikinci uygulamayla tedavi oranı %92.9'a yükseldi. Sonuç: Tiroid kistlerinin tedavisinde ultrason eşliğinde PEİ uygulaması yüksek başarı oranlarıyla etkili, ucuz ve güvenilir bir tedavi yöntemidir.

Percutaneous ethanol injection into thyroid cysts

Objective: To present the results of 28 patients who were treated by Doppler ultrasound guided percutaneous ethanol injection (PEI) into benign cystic thyroid nodules. Methods: Before percutaneous injection of ethanol, malignancies were excluded with fine needle aspiration biopsy. Volume of the nodule was calculated according to length χ width χ depth χ π/6 formula. During the application, 95% ethanol solution was injected about half of the initial cystic volume. At follow-up nodule diameter, formation of fibrosclerosis and nodule vascularization were evaluated. More than 50% reduction in nodule volume relative to the initial volume was defined success. Results: The success rate with single application of PEI was found 88.5 percent. With administration of the second application of PEI on unsuccessful cases success rate increased to 92.9 percent. Conclusion: Doppler ultrasound-guided PEI injection is a reliable, effective and inexpensive method in the treatment of thyroid cysts with high success rates.

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  • Tanriover O, Comunoglu N, Eren B, et al. Occult papillary thy- roid carcinoma: prevalence at autopsy in Turkish people. Eur J Cancer Prev 2011;20:308-12.
  • De losSantos ET, Keyhani-Rofagha S, Cunningham JJ, Mazzaferri EL. Cystic thyroid nodules. The dilemma of malignant lesions. Arch Intern Med 1990;150:1422-7.
  • Roh JL, Park C 2nd. Treatment of benign thyroid cysts by intra- cystic injection of OK-432. Surgery 2008;144:775-9.
  • Garg MK, Satija L, Khanna SK, Saini JS. Intracystic tetracycline therapy for hypofunctioning cystic thyroid nodules. J Assoc Physicians India 2000;48:891-4.
  • Lee JH, Kim YS, Lee D, Choi H, Yoo H, Baek JH. Radiofrequ- encyablation (RFA) of benign thyroid nodules in patients within completely resolved clinical problems after ethanol ablation (EA). World J Surg 2010;34:1488-93.
  • Dİssing H, Bennedbaek FN, Hegedüs L. Beneficial effect of com- bined aspiration and interstitial laser therapy in patients with benign cystic thyroid nodules: a pilot study. Br J Radiol 2006;79 (948):943-7.
  • Cho YS, Lee HK, Ahn IM, et al. Sonographically guided ethanol sclerotherapy for benign thyroid cysts: result in 22 patients. AJR Am J Roentgenol 2000;174:213-6.
  • Clark OH, Okerlund MD, Cavalieri RR, Greenspan FS. Diagnosis and treatment of thyroid, parathyroid, and thyroglossal duct cysts. J Clin Endocrinol Metab 1979;48:983-8.
  • Jensen F, Rasmussen SN. The treatment of thyroid cysts by ultrasonically guided fine needle aspiration. Acta Chir Scand 1976; 142:209-11.
  • Edmonds CJ, Telle ZM. Thyroid cysts and their managements. Br Med J 1987;295:529-33.
  • Livraghi T, Paracchi A, Ferrari C, Reschini E, Nacchi RM, Bonifaino A. The treatment of autonomous thyroid nodules with percutaneous ethanol injection: 4 year experience. Radiology 1994; 190:529-33.
  • Vergès B, Buffier P, Baillot-Rudoni S, Brindisi MC, Bouillet B, Petit JM. Non-ultrasound-guided ethanol sclerotherapy for the treatment of thyroid cysts. Ann Endocrinol (Paris) 2011;72:203-7.
  • Monzani F, Lippi F, Goletti O, et al. Percutaneous aspiration and ethanol sclerotherapy for thyroid cysts. J Clin Endocrinol Metab 1994;78:800-2.
  • Bartos M, Pomorski L, Narebski J. The treatment of solitary thy- roid nodules in non-toxic goiter with 96% ethanol injections. [Article in Polish] Wiad Lek 1999;52:432-40.
  • Bennedbaek FN, Hegedüs L. Treatment of recurrent thyroid cysts with ethanol: a randomized double-blind controlled trial. J Clin Endocrinol Metab 2003;88:5773-7.
  • Sung JY, Baek JH, Kim YS, et al. One-step ethanol ablation of vis- cous cystic thyroid nodules. AJR Am J Roentgenol 2008;191:1730- 3.
  • Del Prete S, Caraglia M, Russo D, et al. Percutaneous ethanol injection efficacy in thetreatment of large symptomatic thyroid cys- tic nodules: ten-year follow-up of a large series. Thyroid 2002;12: 815-21.
  • Chu CH, Chuang MJ, Wang MC, Lam HC, Lu CC, Lee JK. Sclerotherapy of thyroid cystic nodules. J Formos Med Assoc 2003; 102:625-30.
  • Kim JH, Lee HK, Lee JH, Ahn IM, Choi CG. Efficacy of sono- graphically guided percutaneous ethanol injection for treatment of thyroid cysts versus solid thyroid nodules. AJR Am J Roentgenol 2003;180:1723-6.
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  • Please cite this article as: Çetin B, Duman K, Karapınar U, Sa¤lam Ö, Dursun E. Percutaneous ethanol injection into thyroid cysts. J Med Updates 2013;3(3):142-145.
ENT Updates-Cover
  • ISSN: 2149-7109
  • Başlangıç: 2015
  • Yayıncı: Prof.Dr.Murat Demir
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