Defne Gümüş, Derya Bayırlı Turan, Tuba Kuruoğlu, Fatma Kalaycı, Kıvanç Şerefhanoğlu

Üçüncü basamak bir hastaneye başvuran hastalarda HBsAg ve anti-HCV seroprevalansı: Altı yıllık retrospektif veriler

Amaç: Çalışmamızda hastanemize başvuran hastalarda Hepatit B ve Hepatit C seroprevalansının yaş gruplarına göre yıllar içindeki değişimini ve dağılımını araştırmayı amaçladık. Gereç ve Yöntem: İstanbul'da üçüncü basamak hastaneye altı yıl boyunca başvuran hastalar retrospektif olarak değerlendirildi. Aynı yıl içinde birden fazla başvuru yapan hastaların mükerrer sonuçları çalışma dışı bırakıldı. Kadın ve erkek hastalar 0-14, 14-25, 25-49 ve 49 yaş üzeri olmak üzere dört yaş grubuna ayrıldı. HBsAg ve anti-HCV testleri için elektrokemilüminesans yöntemi (Roche Cobas 6000, Almanya) kullanıldı. Bulgular: HBsAg pozitifliği %2,97 ve anti-HCV pozitifliği %1,35 oranında saptandı. HBsAg pozitifliği erkeklerde, antiHCV pozitifliği kadınlarda daha yüksek oranda idi. Anti-HCV ve HBsAg seroprevalansında 6 yıllık periyodda dikkati çekecek artış saptanmadı. HBsAg seroprevalansında özellikle 0-14 ve 14-25 yaş erkek gruplarında yıllar içinde azalma dikkati çekti. Diğer yaş gruplarında HBsAg seroprevalansında yıllar içinde bir azalma saptanmadı. Anti-HCV seroprevalansında ise yıllar içinde dikkati çekecek önemli bir fark saptanmadı.Sonuç: HBsAg pozitifliğinde özellikle 0-14 ve 14-25 yaş erkek gruplarında yıllar içinde azalma dikkati çekti. Diğer yaş gruplarında HBsAg seroprevalansında yıllar içinde bir azalma saptanmadı. Anti-HCV seroprevalansında ise yıllar içinde dikkati çekecek önemli bir fark saptanmadı.

Seroprevalence of HBsAg and anti-HCV for patients who admitted to third step hospital: Six-year retrospective data

Aim: We aimed to investigate the alteration and distribution of seroprevalence of hepatitis B and hepatitis C withinthe years according to age groups in patients who applied to our hospital.Materials and Methods: The patients have been evaluated for six years retrospectively who were admitted to thirdstep hospital in Istanbul. The duplicate results of patients who submitted more than one application within the sameyear were excluded from this study. Male and female patients were divided into four age groups as 0-14, 14-25, 25-49 and over 49 years old. Electrochemiluminescence method (Roche Cobas 6000, Germany) was used for HBsAgand anti-HCV assays.Results: HBsAg positivity was 2.97% and anti-HCV positivity was 1.35%. HBsAg positivity was higher in males, andanti-HCV positivity was higher in females. No significant increase in seroprevalences of anti-HCV and HBsAg wasobserved during the six years observation period. HBsAg seroprevalences decreased in years especially in 0-14 and14-25 year-old male groups. HBsAg seroprevalence was not decreased in the other age groups over the years.There was no significant difference in anti-HCV seroprevalence over the years. HBsAg positivity was higher in malesand anti-HCV positivity was higher in females. Anti-HCV and HBsAg seroprevalence were not significantly differedover the years.Conclusion: It was remarkable that HBsAg positivity rate had decreased over the years especially in 0-14 and 14-25year-old males. Seroprevalence of HBsAg did not decrease in years in other age groups. There was no significantdifference in the seroprevalence of anti-HCV during the measurement period.

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