Sinem ERMİN, Hazal KAYIKÇI, Özgür BATUM, Ufuk YILMAZ

Plevral sıvı kolesterol düzeyinin eksüda ve transüda ayırımındaki rolü Role of pleural fluid cholesterol level in discrimination of transudates and exudates Sinem Ermin¹ Hazal Kayıkçı² Özgür Batum¹ Ufuk Yılmaz³ ¹ Sağlık Bilimleri Üniversitesi, Dr. Suat Seren Göğüs Hastalıkları ve Cerrahisi Eğitim ve

Amaç: Plevral sıvıların tanısında, transüda (T)–eksüda (E) ayrımının yapılması önemlidir. Bu çalışmanın amacı, Light kriterleri ile plevral sıvı kolesterol düzeyini içeren tekli, ikili ve üçlü testlerin, T- E ayırımındaki duyarlılık ve özgüllüğünü belirlemektir. Gereç ve Yöntem: Çalışmaya plevral sıvı nedeniyle başvuran 145 hasta dâhil edildi. Plevral sıvı kolesterol düzeyi (PSKD) ≥45 mg/dL (tekli test); PSKD ≥45 mg/dL veya plevral sıvı LDH düzeyi >kan normal LDH’sının %45 (ikili test); plevral sıvı protein >2,9 g/dL, PSKD ≥45 mg/dL, plevral sıvı LDH düzeyi >kan normal LDH’sının %45 (üçlü test) olarak tanımlandı. Kesin tanıya uygun beklenen plevral sıvı tipi altın standart olarak değerlendirmeye alındı. Bulgular: Çalışmaya alınan 139 hastada, kesin tanıya uygun beklenen plevral sıvı tipi olguların %81’inde eksüda; %19’unda transüda olarak belirlendi. Eksüdatif plevral sıvıyı saptamada, tekli testin kesin tanıya uygun beklenen plevral sıvı tipi ile karşılaştırılmasında iki grup arasında sınırda anlamlılık saptandı (p=0.05). İkili ve üçlü test değerlendirmelerinde ise iki grup arasında istatistiki anlamlı fark saptandı (p

Role of pleural fluid cholesterol level in discrimination of transudates and exudates

Aim: It is important in the diagnosis of pleural effusions is to make a discrimination between transudates (T) and exudates (E). The purpose of our study is to measure the sensitivity and specificity of Light’s criteria and single,double and triple tests including pleural liquid cholesterol in discrimination of T-E. Materials and Methods: This study included 145 patients. Pleural fluid cholesterol>45 mg/dL(single test) or pleural fluid LDH greater than 45% upper limit of normal blood LDH was defined as exudates (double test). Pleural fluid protein >2.9 g/dL or pleural fluid cholesterol>45 mg/dL or pleural fluid LDH greater than 45% upper limit of normal blood LDH was defined as exudates (triple test). The expected type of pleural effusion to be appropriate for definitive diagnosis was considered as the gold standard. Results: When a total of 139 patients were grouped according to their definitive diagnosis, the expected type of pleural effusion was determined as exudative in 81% and transudative in 19%. In the detection of exudative pleural fluid, single test was compared with definitive diagnosis and borderline significance was found between the two groups (p=0.05). In the double and triple test assessments, there was a statistically significant difference between the two groups in both analyzes (p

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