Effects of chronic renal insufficiency on risk factors and results of endoscopy in patients with upper gastrointestinal system bleeding

Aim: Acute upper gastrointestinal system (GIS) bleeding is one of the leading causes of mortality and morbidity. Presence of concomitant disease in upper GIS bleeding is a mortality-associated risk factor, and chronic renal insufficiency (CRI) is one of these concomitant diseases. In the present study, patients with CRI, who had upper GIS bleeding and been treated as inpatient between January 2016 and January 2017 at Tepecik Training and Research Hospital Clinic of Gastroenterology, and the patients that had upper GIS bleeding without renal insufficiency were comparatively investigated in terms of demographic characteristics, presence of concomitant disease, drug usage, endoscopic results, Forrest classification, and need for endoscopic intervention and mortality. Materials and Methods: A total of 194 patients were retrospectively evaluated. The CRI group with a glomerular filtration rate (GFR) lower than 60 mL/min/1.73 m2 comprised 90 patients, whereas the control group with a GFR of 60 mL/min/1.73 m2 and higher comprised 104 patients. Results: As the result of the study, it was determined that CRI group was older and 96% of the patients had a concomitant disease. Drug usage rate was higher than the control group with aspirin used most frequently. Endoscopy was performed on Day 1 in more than 70% of the cases. Conclusion: Hospital mortality rate was higher in CRI group (5.66% vs 2.88%, p=0.475) with lower total mortality rate found in the present study as compared to the literature.

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