YELİZ ÇAĞAN APPAK, SEMİN AYHAN, HASAN ERHUN KASIRGA

Co-existence of celiac disease and eosinophilic esophagitis: Is it a coincidence for the two diseases?

Çölyak hastalığı ve eozinofilik özefajit genellikle ayrı gastrointestinal hastalıklar olarak değerlendirilmekle beraber birliktelikleri beklenenden çok daha fazladır. Burada pozitif çölyak serolojisi olan ve endoskopik patoloji sonucunu ile Marsh sınıflamasına göre çölyak hastalığı tip 3c olarak değerlendirilen 5 yaşında kız hastayı sunmaktayız. Diğer taraftan hastanın özefagus mukoza biyopsi örneklerinde her sahada 100 den fazla eozinofilisi mevcuttu ve hasta eozinofilik özefajit olarak da değerlendirildi. Çölyak hastalığı ve eozinofilik özefajit arasındaki ilişki kesin değildir. Bununla birlikte çölyak hastalığı olan çocuklarda eozinofilik özefajit birlikteliğine dikkat edilmesi gerekmektedir

Çölyak hastalığı ve eozinofilik özefajit birlikteliği: Bu iki hastalık için bir tesadüf mü?

Celiac disease and eosinophilic esophagitis are usually considered to be separate gastrointestinal diseases; however, it appears that they may coexist more often than would be expected. We report the case of a 5-year-old girl who had positive celiac serology and was assessed as having type 3c celiac disease according to the Marsh classification with endoscopic pathology. However, the patients eosinophils were more than 100 per high-power field in esophageal mucosal biopsy specimens and she was evaluated as having eosinophilic esophagitis as well. The relationship between celiac disease and eosinophilic esophagitis is not clear. Nevertheless, coexistence of eosinophilic esophagitis needs to be considered in children with celiac disease.

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