Mehmet ERDOĞAN, Nihal ERDEM, A. Ömer ÖZÜTEMİZ

A common variable immune deficiency (CVID) case with chronic diarrhea: A case report

Tekrarlayan diare ve solunum yolu enfeksiyonu nedeniyle tetkik edilen hastada serum immunglobulin eksikliği saptandı. Immune yetmezliği olan hastada flowstometrik değerlendirmeden sonra genel değişken immun yetersizlik tanısı kondu ve aylık intravenöz immunglobulin tedavisi başlandı. Parazitolojik analizde Giardiasis bulundu. On aylık izleme sırasında immunglobulin desteği ve giardiazis tedavisi sonrası diare geriledi ve hasta tekrar solunum yolu enfeksiyonu geçirmedi.

Anahtar Kelimeler:

Giardia, Erkek, Tedavi sonucu, Erişkin, İshal, Kronik hastalık, Solunum yolu enfeksiyonları, İmmünoglobulinler, İmmün yetmezlik sendromları

Kronik ishal ile seyreden bir genel (Yaygın) değişken immun yetmezlik olgusu: Olgu sunumu

The patient with recurrent episodes of diarrhea and respiratory tract infections was analysed and determined to have immunoglobulin deficiency.The patient was diagnosed as Common Variable Immuno deficiency after flowcytometric assessment and immunoglobulin treatment was started. Giardiasis was found in the parasitologic analysis. During the 10 month follow-up after immunoglobulin replacement and the traeatment of giardiasis, the diarrhea disappeared and the patient didnot have respiratory tract infections.

Keywords:

Giardia, Male, Treatment Outcome, Adult, Diarrhea, Chronic Disease, Respiratory Tract Infections, Immunoglobulins, Immunologic Deficiency Syndromes,

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1. Borre -Sinoussi F, Cherman JC, Rey F, et al. Isolatıon of a T lymphocytic retrovirüs from a patient at risk for acquired immune deficiency syndrome(AIDS). Science 1983;220:868-871
2. Rosen FS, Cooper MD, Wedgwood RJP.The primary immunodeficiencies. N Engl J Med 1984;311:300-310
3. Hanson LA, Brandtzaeg P. The mucosal defense system. lırStiehm RT .Fulginite V.end. Immunologic Disorders in ınfants and Chıldren 2 nd Ed. Philadelphia:WB Saunders Company,1980;pp 137-164.
4. Hermens PE, Diaz-Buxo JA, Stobo JD, Idiopatk late -onset immunoglobulin deficiency. Am J Med 1976;221-232
5. Moore GT , Cross WM, Mcguıre D, et al. Epidemic giardiasis at a ski resort. N Engl J Med 1969;281:402-407
6. Pediatric Clinics of North America Volume 47, Number 6, December 2000 Copyright C 2000 W.B.Saunders Company (1225- 1252),1355-1369)
7. Schmerin MJ, Jones TC, Klein H. Giardiasis:association with homosexuality. Ann Intern Med 1978;88:801-803