Evidence based neonatal medicine: dilemmas remain

Abstract. Evidence-based medicine has become increasingly important over the years. Getting research evidence into practice is a necessity in current practice. It has to be kept in mind that every patient population has its own special characteristics and this may make the best available research evidence sometimes not the best option for that particular population. Some examples of how the characteristics of a population may influence important evidence-based treatment decisions are discussed.Key words: Evidence-based medicine, beractant, poractant, palivizumab, umbilical artery catheterisations

Keywords:

Evidence-based medicine, beractant, poractant palivizumab, umbilical artery catheterisations,

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Prescott WA Jr, Doloresco F, Brown J, Paladino JA. Cost effectiveness of respiratory syncytial virus prophylaxis: a critical and systematic review. Pharmacoeconomics 2010; 28: 279-293.
Chan PW, Abdel-Latif ME. Cost of hospitalization for respiratory syncytial virus chest infection and implications for passive immunization strategies in a developing nation. Acta Paediatr 2003; 92: 481-485.
Van Rostenberghe HL, Kew ST, Hanifah MJ. RSV and bronchiolitis. Arch Dis Child Fetal Neonatal Ed 2006; 91: F154.
Bala P, Ryan CA, Murphy BP. Hospital admissions for bronchiolitis in preterm infants in the absence of respiratory syncytial virus prophylaxis. Arch Dis Child Fetal Neonatal Ed 2005. 90F92.
Simoes EA, Groothuis JR, Carbonell-Estrany X, et al. Palivizumab Long-Term Respiratory Outcomes Study Group. Palivizumab prophylaxis, respiratory syncytial virus, and subsequent recurrent wheezing. J Pediatr 2007; 151: 34-42, 42.e1.
Barrington KJ. Umbilical artery catheters in the newborn: effects of position of the catheter tip. Cochrane Database of Systematic Reviews 1999, Issue 1. Art. No.: CD000505. DOI: 10.1002/14651858.CD000505
Harris M, Little G. Umbilical artery catheters: High, low, or no. Journal of Perinatal Medicine 1978; 6: 15-21.
Kempley ST, Bennett S, Loftus BG, et al. Randomized trial of umbilical arterial catheter position: Clinical outcome. Acta Paediatrica 1993; 82: 173-176.
Mokrohisky ST, Levine RL, Blumhagen JD, et al. Low positioning of umbilical-artery catheters increases associated complications in newborn infants. New England Journal of Medicine 1978; 299: 561-564.
Stork EK, Carol WA, Kleigman RM, Fanaroff AA. Neonatal hypertension appears unrelated to aortic catheter position. Pediatric Research 1984; 18: 321A.
Umbilical Artery Catheter Trial Study Group. Relationship of intraventricular hemorrhage or death with the level of umbilical artery catheter placement: A multicenter randomized clinical trial. Pediatrics 1992; 90: 881-887.
Wesstrom G, Finnstrom O, Stenport G. Umbilical artery catheterization in newborns. I Thrombosis in relation to catheter type and position. Acta Paediatrica Scandinavica 1979; 68: 575-581.