Diagnostic Value of Endobronchial Ultrasonography in Lung and Mediastinal Lesions

EBUS (Endobronchial Ultrasonography) is a highly invasive diagnostic method with high rate of diagnosis by needle aspiration from mediastinal lymph nodes or masses, extremely low complication rate and costly compared to other invasive methods. In this study, we aimed to determine the contribution of endobronchial ultrasound guided needle aspiration to the diagnosis of lung and mediastinal diseases. Patients with mediastinal masses, mediastinal lymph nodes and lung parenchymal masses who underwent Fine-Needle Aspiration Biopsy (FNAB) accompanied by EBUS between January 2016 and January 2018 were evaluated retrospectively. 170 (65.1%) of 261 patients who underwent aspiration biopsy with EBUS were male; 91 (34.9%) patients were female. While the diagnosis was reached in 154 (90%) of 170 male patients who underwent EBUS, it was observed that the diagnosis was reached in 81 (89.0%) of 91 female patients. There was no statistically significant difference between gender and diagnosis (p value 0.685). The average age of the patients was 59.8. There was no statistical difference between age and diagnosis (p: 0.836). While 73 (31.06%) of 98 (41.7%) malignant patients were non -small cell, 20 (8.51%) patients had small cell lung cancer, 5 (2.12%) patients had metastatic tumor. 137 Beni gn lesion was detected in the patient (58.3%). Of the 28 patients with granulomatous inflammation, 14 (5.95%) were found to have sarcoidosis and 14 (5.95%) had tuberculosis. In addition, anthractosis in 52 (22.12%) patients, inflammation in 45 (19.14%) patients, and normal tissue in 12 (5.1%) patients. The remaining patients were non-diagnostic. As a result; EBUS distinguishes between malignant/benign masses and granulomatous disease with material taken from leucions in lung and mediastinum. The diagnosis rate is high, the complication rate is low and the cost is cheaper compared to other invasive methods and now it is used more frequently.

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1. Yasufuku K, Chiyo M, Sekine Y, et al. Realtime endobronchial ultrasound-guided transbronchial needle aspiration of mediastinal and hilar lymph nodes. Chest 2004; 126: 122- 128.

2. Figueiredo VR, Jacomelli M, Rodrigues AJ, Canzian M, Cardoso PF, Jatene FB. Current status and clinical applicability of endobronchial ultrasound-guided transbronchial needle aspiration. J Bras Pneumol 2013; 39: 226-237.

3. Nakajima T, Yasufuku K, Yoshino I. Current status and perspective of EBUS-TBNA.Gen Thorac Cardiovasc Surg 2013; 61: 390-396.

4. Kinsey CM, Arenberg DA. Endobronchial Ultrasoundguided Transbronchial Needle Aspiration for Non-Small Cell Lung Cancer Staging. Am J Respir Crit Care Med 2014; 189: 640-649.

5. De Leyn P, Dooms C, Kuzdzal J, et al. Revised ESTS guidelines for preoperative mediastinal lymph node staging for non-smallcell lung cancer. Eur J Cardiothorac Surg 2014; 45: 787-798.

6. Parmaksız E T, Caglayan B, Salepci B, et al. The utility of endobronchial ultrasoundguided transbronchial needle aspiration in mediastinal or hilar lymph node evaluation in extrathoracic malignancy: Benign or malignant? Annals of ThoracicMedicine 2012; 7: 210-214.

7. Caglayan B, Salepci B, Dogusoy I, et al. The role of convex probe endobronchial ultrasound guided transbronchial needle aspiration in the diagnosis of malignant mediastinal and hilar lymph nodes. Iran J Radiol 2012; 9: 183-189.

8. Özgül M A, Çetinkaya E, Tutar N, Özgül G, Onaran H, Bilaçerog lu S. Endobronchial ultrasound- guided transbronchial needle aspiration for the diagnosis of intrathoracic lymphadenopathy in patients with extrathoracic malignancy: A study in a tuberculosis endemic country. Journal of Cancer Research and Therapeutics 2013; 9: 416-421.

9. El-Zammar OA, Katzenstein ALA. Pathological diagnosis of granulomatous lung disease: a review. Histopathology 2007; 50: 289-310.

10. Çag layan B, Salepçi B, Fidan A, et al. Sensitivity of convex probe endobronchial sonographically guided transbronchial needle aspiration in the diagnosis of granulomatous mediastinal lymphadenitis. J Ultrasound Med 2011; 30: 1683-1639.

11. Cetinkaya E, Gunluoglu G, Ozgul A, et al. Value of real-time endobronchial ultrasoundguided transbronchial needle aspiration. Ann Thorac Med 2011; 6: 77-81.

12. Navani N, Molyneaux PL, Breen RA, et al. Utility of endobronchial ultrasound-guided transbronchial needle aspiration in patients with tuberculous intrathoracic lymphadenopathy: a multicentre study. Thorax 2011; 66: 889-893.

13. Yasufuku K: Endoscopic staging of lung cancer. In: Beamis JF, eds. Interventional Pulmonary Medicine, 2nd ed. New York: Informa Healthcare 2010; 84-96.

14. Lee HS, Lee GK, Lee HS, et al. Real-time endobronchial ultrasoundguided transbronchial needle aspiration in mediastinal staging of non-small cell lung cancer: How many aspirations per target lymph node station? Chest 2008; 134: 368-374.

15. Chin R, McCain TW, Lucla MA, et al. Transbronchial needle spiration in diagnosing and staging lung cancer. How many aspirates are needed? Am J Respir Crit Care Med 2002; 166: 377-381.

16. Bartheld MB, Breda AV, Annema JT, Complication Rate of Endosonography (Endobronchial and Endoscopic Ultrasound): A Systematic Review. Respiration 2014; 87: 343-351.

17. von Bartheld MB, van Breda A, Annema JT, et al. Complication rate of endosonography (endobronchial and endoscopic ultrasound): a systematic review. Respiration 2014; 87: 343- 351.37.

18. von Bartheld MB, Annema JT. Endosonography-related mortality and morbidity for pulmonary indications: a nationwide survey in the Netherlands. Gastrointest Endosc 2015; 82: 1009-1015
Eastern Journal of Medicine-Cover
  • ISSN: 1301-0883
  • Başlangıç: 1996
  • Yayıncı: ERBİL KARAMAN
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