Konjonktival Pterjium Etyopatogenezinde Sistemik İnflamasyonun Rolünün Değerlendirilmesi

Amaç: Konjonktival pterjiumlu hastalarda hemogram parametreleri ve kan temelli sistemik inflamasyon belirteçlerinindüzeylerinin incelenmesidir.Gereç ve Yöntemler: Çalışmaya konjonktival pterjiumu olan 30 hasta ve yaş-cinsiyet uyumlu 31 sağlıklı gönüllü dahiledildi. Tüm olgulara detaylı oftalmolojik muayene yapıldı. Ayrıca pterjium grubundaki olgularda pterjiumderecelendirilmesi yapıldı. Tüm olgulardan serum örnekleri toplandı ve nötrofil/lenfosit oranı, platelet/lenfosit oranı vesistemik immün-inflamasyon indeksi hesaplandı. Gruplar arasında nötrofil sayı-yüzdesi, lenfosit sayı-yüzdesi,hemoglobin, eritrosit sayısı, lökosit sayısı, ortalama trombosit hacmi, eritrosit dağılım genişliği, trombosit sayısı,nötrofil/lenfosit oranı, platelet/lenfosit oranı, sistemik immün-inflamasyon indeksi arasında ilişki olup olmadığıincelendi. İstatistiksel analizde Ki-kare testi, Bağımsız örneklemler t-testi, Mann-Whitney U testi, Pearson ve Spearmankorelasyon analizleri kullanıldı. P

To Evaluate the Role of Systemic Inflammation on Conjunctival Pteryigum Etiopathogenesis

Aim: To assess the complete blood count parameters and blood-based systemic inflammatory markers in patients with conjunctival pterygium. Materials and Methods: Thirty patients with conjunctival pterygium and 31 age and sex-matched control subjects included in the study. All patients underwent detailed ophthalmologic examination. Pterygium was also graded in pterygium group. Serum samples were obtained from all subjects, and neutrophillymphocyte ratio, plateletlymphocyte ratio and systemic immune-inflammation index were calculated. It is examined whether or not there exits an association between groups in terms of neutrophil countpercentage, lymphocyte countpercentage, hemoglobin, red blood cell count, white blood cell count, mean platelet volume, red cell distribution width, platelet count, neutrophillymphocyte ratio, plateletlymphocyte ratio and systemic immune-inflammation index. The statistical assessment was performed with the assistance of Pearson’s Chi-square test, Independent samples t-test, Mann-Whitney U test, Pearson and Spearman correlation analysis. P

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