İskemik İnmeli Genç Hastaların Demografik, Etyolojik ve Risk Faktörleri

Amaç: Genç iskemik inmeli hastaların etyopatogenezini ve vasküler risk faktörlerinideğerlendirmektir.Yöntem: Elli üç genç iskemik inmeli hasta retrospektif olarak incelendi.Hastalar TOAST sınıflamasına göre değerlendirildi. Tıbbi öykülerinde sigara, alkol alımı, oralkontraseptif, düşük öyküsü, gebelik, hipertansiyon diyabetes mellitus ve ateroskleroz sorgulandı.Bulgular: Elli üç hastanın 33’ü erkek (%43.4), 30’u kadındı (%56.6). Hastaların etyolojisinde17’sinde (%32.1) büyük damar hastalığı, 12’sinde (%22.6) kardiyoemboli ve 11’inde (%20.8)diğer nedenler tespit edilirken 3 (%5.7) hastada neden bulunamadı.Sonuç: İnme geçirme riski olan genç hastalarda risk faktörleri belirlenip gerekli önlemleralınarak genç inmeli hastaların insidansının azaltılarak buna bağlı gelişebilecek mortalite veözürlülüğün engellenebileceği kanaatindeyiz

Demographic and Etiologic Data and Risk Factors of Young Stroke Patient

Purpose: Was to evaluate the etiopathogenesis and vascular risk factors in young patients withischemic stroke.Methods: Fifty-three young patients (age between 17-45 years) with ischemic stroke wereanalysed retrospectively. The cases were classified according to TOAST classification. Inmedical history, smoking, alcohol taking, oral contraceptive, abortion history, pregnancy,hypertension, diabetes mellitus, and atherosclerosis has been evaluated.Results: Of the 53 patients, 23 (43.4%) were males and 30 (56.6%) were females. The riskfactors described for the etiology of stroke was found to large vessel disease 17 (32.1%), cardioemboli 12 (22.6%), small vessel disease 11 (20.8%), other factors 11 (20.8%) and undeterminedfactors 3 (5.7%).Conclusions: We believe that may reduce the incidence of stroke in the young patients bydetermined risk factors and taking the necessary measures, hereby may prevent mortality anddisability in the patients who have risk for stroke

___

  • Medin J, Nordlund A, Ekberg K: Increasing stroke incidence in Sweden between 1989 and 2000 among persons aged 30 to 65 years: evidence from the Swedish Hospital discharge register. Stroke. 35: 1047-1051, 2004.
  • Evers SM, Struijs JN, Ament AJ, Van Genugten ML, Jager JH, Van den Bos GA: International comparison of stroke cost studies. Stroke. 35:1209-1215, 2004.
  • Correia M, Silva MR, Matos I, et al: Prospective community- based study of stroke in Northern Portugal: Incidence and case fatality in rural and urban populations. Stroke. 35: 2048– 2053, 2004.
  • Putaala J, Metso AJ, Metso TM, et al: Analysis of 1008 consecutive patients aged 15 to 49 with first-ever ischemic stroke: the Helsinki young stroke registry. Stroke. 40: 1195– 1203, 2009.
  • Baptista MV, Ferreira S, Pinho-E-Melo T, et al: Mutations of the GLA gene in young patients with stroke: the PORTYSTROKE study-screening genetic conditions in Portuguese young stroke patients. Stroke. 41: 431–436, 2010.
  • Marini C, De Santis F, Sacco S, et al: Contribution of atrial fibrillation to incidence and outcome of ischemic stroke: results from a population-based study. Stroke. 36: 1115–1119, 2005.
  • Arnold M, Halpern M, Meier N, et al: Age-dependent differences in demographics, risk factors, co-morbidity, etiology, management, and clinical outcome of acute ischemic stroke. J Neurol. 255: 1503–1507, 2008.
  • Rouanet F, Sibon I, Goizet C, Renou P, Meissner W: Pour le groupe de travail de la SFNV: Bilan étiologique des infarctus cérébraux dusujet jeune. Propositions du groupe de travail de la société française neuro-vasculaire.Rev Neurol. 165: 283– 288, 2009.
  • Cerrato P, Grasso M, Imperiale D, et al: Stroke in young patients:etiopathogenesis and risk factors in different age classes. Cerebrovasc Dis. 18: 154–159, 2004.
  • Lipska K, Sylaja PN, Sarma PS, et al: Risk factors for acute ischaemic stroke in young adults in South India. J Neurol Neurosurg Psychiatry. 78: 959–963, 2007.
  • Mehndiratta MM, Agarwal P, Sen K, Sharma B: Stroke in young adults: a study from a university hospital in north India. Med Sci Monit. 10: 535–541, 2004.
  • Dharmasaroja PA, Muengtaweepongsa S, Lechawanich C, Pattaraarchachai: J: Causes of ischemic stroke in young adults in Thailand: a pilot study. J Stroke Cerebrovasc Dis. 20: 247-250, 2011
  • Samiullah S, Humaira M, Hanif G, Ghouri AA, Shaikh K: Etiological patterns of stroke in young patients at a tertiary care hospital. J Pak Med Assoc. 60: 201–204, 2010.
  • Adams HP Jr, Bendixen BH, Kappelle LJ et al: 3rd. Classification of subtype of acute ischemic stroke.Definitions for use in a multicenter clinical trial.TOAST. Trial of Org 10172 in Acute StrokeTreatment. Stroke. 24:35-41, 1993.
  • Varona JF, Bermejo F, Guerra JM, Molina JA: Long-term prognosis of ischemic stroke in young adults. Study of 272 cases.J Neurol. 251:1507–1514, 2004
  • Demir A. Şef: Çelebi A: Akut iskemik inme geçiren genç yaş grubundaki hastalarda risk faktörleri ve etyolojik sebeblerin retrospektif incelenmesi. T.C. Sağlık Bakanlığı Taksim Eğitim Ve Araştırma Hastanesi Nöroloji Servisi, Uzmanlık Tezi. İstanbul, 30-36, 2006.
  • Adnan I.Q, Kamran S, Manesh P, Robert S, et al: Stroke in young black patients. Risk factors, subtype and prognosis. Stroke. 26:1995-1998, 1995
  • Leys D, Bandu L, Henon H, et al: Clinical outcome in 287 consecutive young adults (15 to 45 years) with ischemic stroke. Neurology. 59: 26-33, 2002.
  • Lee TH, Hsu WC, Chen CJ, Chen ST: Etiologic study of young ischemic stroke in Taiwan. Stroke. 33: 1950-1955, 2002
  • Putaala J, Curtze S, Hiltunen S, Tolppanen H, Kaste M, Tatlisumak T: Causes of death and predictors of 5-year mortality in young adults after first-ever ischemic stroke: the Helsinki Young Stroke Registry. Stroke. 40: 2698-2703, 2009.
  • Balci K, Utku U, Asil T, Celik Y: Ischemic stroke in young adults: risk factors, subtypes, and prognosis. Neurologist. 17:16-20, 2011.
  • Rohr J, Kittner S, Feeser B, et al: Traditional risk factors and ischemic stroke in young adults: the Baltimore–Washington Cooperative Young Stroke Study. Arch Neurol. 53: 603–607, 1996
  • You RX, McNeil JJ, O’Malley HM, et al: Risk factors for stroke due to cerebral infarction in young adults. Stroke. 28: 1913–1918, 1997.
  • Çelebi H.H,Şef Işık N: Genç iskemik inmelerde risk faktörleri ve etyolojik nedenlerle arter alanları ve prognoz ilişkisi. Uzmanlık tezi. İstanbul, 41-53, 2005
  • Kwon S, Kim JS, Lee JH, Lee MC: Ischemic stroke in Korean young adults. Acta Neurol Scand. 101: 19-24, 2000.
  • Tsong-Hai L, Wen-Chuin H, Chi-Jen C, Sien-Tsong C: Etiologic study of young ischemic stroke in Taiwan. Stroke. 33:1950-1955, 2002
  • Musolino R, La Spina P, Granata A, et al: Ischaemic stroke in young people: a prospective and long-term follow-up study. Cerebrovasc Dis. 15: 121–128, 2003
  • Naess H, Nyland HI, Thomassen L. Ve ark. Incidence and short-term outcome of cerebral infarction in young adults in Western Norway. Stroke. 33:2105-2108, 2002.
  • Kristensen B, Malm J, Carlberg B, et al: Epidemiology and etiology of ischemic stroke in young adults aged 18 to 44 years in Northern Sweden. Stroke. 28:1702-1709, 1997
Düzce Tıp Fakültesi Dergisi-Cover
  • Yayın Aralığı: Yılda 3 Sayı
  • Başlangıç: 1999
  • Yayıncı: Düzce Üniversitesi Tıp Fakültesi
Sayıdaki Diğer Makaleler

Off-Pump ile On-Pump Koroner Bypass Cerrahisinde İnflamatuar Yanıtın Karşılaştırılması

Hikmet Selçuk GEDİK, Gökhan LAFCI, Adnan YALÇINKAYA, Adem İlkay DİKEN, Kerim ÇAĞLI, Kemal KORKMAZ

Pediatrik Yaşta Bilgisayarlı Tomografi Uygulamalarında Radyasyon Dozunu Azaltma Stratejileri

Hasan ÇEÇE, Özlem TÜRKSOY, Sema YILDIZ

Nodüler Guatr Tanısı Almış Hastaların Tiroid Hücrelerinin AgNOR Sayısı / Çekirdek ve Toplam AgNOR Alanı / Çekirdek Alanı Oranının Değerlendirilmesi

Nurhan CÜCER, Murat OKTAY, Yusuf AYDIN, Recep ERÖZ

skemik Ön Koşullanma ve Sonradan Koşullanma Mekanizmalarından Biri Olarak Kalsiyum

Demet ŞENGÜL, İlker ŞENGÜL

İskemik İnmeli Genç Hastaların Demografik, Etyolojik ve Risk Faktörleri

Ertugrul UZAR, Mehmet Uğur ÇEVİK, Yavuz YÜCEL, Sebiha CANSEVER, Adalet ARIKANOĞLU, Faysal EKİCİ, Nebahat TAŞDEMİR, Abdullah ACAR

Eskişehir Osmangazi Üniversitesi Tıp ve Mühendislik Fakültesi Öğrencilerinin Cinsel Yolla Bulaşan Hastalıklar ve Aile Planlaması Konusundaki Bilgi ve Tutumlarının Değerlendirilmesi

Sinan ÖZALP, Hüseyin Mete TANIR, Halil ILGIN, Bade ILGIN, Ahmet KARATAŞ

Beden Eğitimi ve Spor Yüksekokulu Öğrencilerinin Doping Kullanımına Bakışları ve Etik

Özgür KARATAŞ, Hakan ÇEVRİM, Mehmet KARATAŞ

Transport Sırasında Balon Valf Sistemiyle Ventilasyon Uygulanırken Gelişen Ani Tansiyon Pnömotoraks

Özkan ÖNAL, A Gülsün PAMUK, Seda B AKINCI, Ülkü AYPAR, İ Aydın ERDEN

Deneysel Karbon Tetraklorür Zehirlenmesinde Akciğer Doku Hasarı ve Melatonin Hormonunun Koruyucu Rolü: Işık Mikroskobik ve Biyokimyasal Bir Çalışma

Burak GÜLCEN, Murat Abdülgani KUŞ, Serdar ÇOLAKOĞLU, Murat ÖGETÜRK, İlter KUŞ, Mehmet Akif ERSOY, Ömür KARACA

Nadir Bir Kombinasyon: Miyokard İnfarktüsü ve Serebral İskemi

Serkan BULUR, Nurten ERCAN, Ramazan BÜYÜKKAYA, Süber DİKİCİ