Esra KABADAYI ŞAHİN, Gökçen TURAN, Salim NEŞELİOĞLU, SERDAR SÜLEYMAN CAN, MURAT İLHAN ATAGÜN

Thiol-disulphide homeostasis in patients with general anxiety disorder and panic disorder

Objective: The aim of this study was to evaluate the dynamic thiol-disulphide homeostasis as a novel oxidative stress parameter in newly diagnosed and medication-naive general anxiety disorder (GAD) and panic disorder (PD) patients. Method: Medication-naive patients with GAD (n=21) or PD (n=23) and healthy individuals (n=23) were enrolled. Patients were administered a sociodemographic form, Beck Depression Inventory, and Beck Anxiety Inventory. Routine biochemical parameters, native thiol, total thiol, and disulphide parameters were measured in all patients and healthy individuals. Results: The native thiol levels of the GAD and PD groups were found significantly lower than those of the control group (p

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