Cerebral venous sinus thrombosis: gender differences in ten years experience

Amaç: Serebral sinus ven trombozu (SSVT) inmenin nadir nedenlerindendir. SSVT kadınlarda erkekleklere göre üçe bir oranında daha sık görülür. Bu kadın baskınlığı cinsiyete özgü rik faktörlerine bağlanmaktadır. Hastaların çoğunda semptomlar günler veya haftalar içinde yerleşmektedir. Bazı hastalarda klinik görünüm nonspesifik olmaktadır. Yöntem: Haseki Eğitim ve Araştırma Hastanesinde 2001-2011 yılları arasında cranial MR ve MR venografi ile tanısı doğrulanarak SSVT tedavisi almış hasta kayıtlarını inceledik. Çalışmaya otuz dört hasta dahil edildi. Kadın/ erkek oranı 3.25/1 idi. Hastaların demografik özelliklerini, komorbid durumlarını, klinik görünümlerini, nöroradyolajik bulgularını inceledik. Bulgular: Çalışmaya otuz dört hasta dahil edildi. Başağrısı hastaların %47.1’inde (n=16) izole olmak üzere tüm hastalarda mevcuttu. Semptomların başlangıcı hastaların %52.9’unda (n=18) subakut, %29.4’ünde (n=10) kronik, %17.6’sında (n=6) akut idi. Tüm hastaların %76.5’i (n=26) kadındı. Her iki cinsiyette de en sık etkilenen sinus transvers sinus olarak saptandı (20 kadın ve 8 erkek). Başvurudaki en sık semptom kadınlarda başağrısı (%43.78) iken, erkeklerde intracranial hipertansiyon (%34.78) idi. Cinsiyete özgü risk faktörü saptanan kadın hastalarımızdan %26.92’si (n=7) doğum control hapı kullanmakta, %15.38’i (n=5) ise gebelik veya lohusa dönemindeydi. Sonuç: Klinik görünüm ve risk faktörleri açısından kadın ve erkeklerde farklılıklar olduğunu gözlemledik.

Serebral sinus ven trombozu: On yıllık tecrübede cinsiyet farklılıkları

Objective: Cerebral venous sinus thrombosis (CVST) is an uncommon subtype of stroke. CVST is much more common in women than men with a ratio of three to one. This women preponderance is attributed to gender-specific risk factors (GSRF). In many patients, symptoms develop over days or weeks. In some patients, clinical presentations are nonspesific. Patients and Methods: We reviewed the records of patients with CVST treated at Neurology department of Haseki Training and Research Hospital between 2001-2011, which diagnoses were confirmed with cranial magnetic resonance imaging (MRI) and magnetic resonance venography (MRV). Thirty- four patients were included the study. Women/men ratio was 3.25/1. We analyzed the demographic features, comorbid conditions, clinical presentation, neuroradiological findings. Results: Thirty- four patients were included the study. Headache was present in all patients and it was present as isolated in 47.1% (n=16) of the patients. In 52.9% (n=18) of the patients onset of the symptoms were subacute, 29.4% (n=10) chronic, 17.6 (n=6) acute. Of all patients, 76.5% (n=26) were women. Transverse sinus was the mostly affected sinus as either isolated or with the other CSVT in both groups (in 20 women and 8 men). The most common presentation symptom (43.78%) in women was headache whereas; it was intracranial hypertension (34.78%) in men. Half of our women patients with GRSF; 7 (26.92%) women were oral contraceptives user and 5 (15.38%) women were in pregnancy or puerperium period. Conclusion: We have found differences between women and men in the presentation and risk factors.

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Düşünen Adam - Psikiyatri ve Nörolojik Bilimler Dergisi-Cover
  • ISSN: 1018-8681
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 1984
  • Yayıncı: Kare Yayıncılık
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