Mesut SİPAHİ, Halil SERİN, Mustafa ERKOÇ, Çiğdem KANTEKİN, Ergin ARSLAN, Hasan BÖREKÇİ

Vücut kompozisyon parametreleri ile nonalkolik hepatosteatoz ilişkisi

Giriş: Obezite ile sıkı korelasyonu bulunan Nonalkolik yağlı karaciğer hastalığı (NYKH) sosyal statünün iyileşmesi ile birlikte dünya çapında yaygın olarak izlenen bir hastalıktır. Vücut kompozisyonu çalışmaları obezite tedavisi takibinde kullanılmaktadır. Vücut kitle indeksi (VKI) ile hepatosteatozis (HS) arasındaki ilişki iyi bilinmektedir. Çalışmamızda vücut kompozisyon parametrelerinin (VKP) hepatosteatoz teşhisindeki etkinliğinin dual bioimpedans analizör (BIA) kullanılarak araştırılması amaçlanmıştır.Yöntemler: NYKH tanısı almış 253 hasta çalışmaya dahil edildi. Yaş, cinsiyet, ve VKI gibi demografik parametreler ve ultrasonografik hepatosteatoz verileri kaydedildi. Total yağ kitlesi ve vücut yüzdesi, yağsız vücut kitlesi, total vücut suyu gibi BCP dual bioimpedans analizör ile değerlendirildi.Bulgular: Hem VKI ve HS, hem de VKP ve HS arasında istatistiksel olarak güçlü korelasyon olduğu izlendi (p<0,05). Fakat HS’ın tanısal değeri açısından VKP ve VKI arasında birbirlerine üstünlüğü yoktu (p>0,05).Sonuç: Bulgularımıza göre, NAFLD hastalığında BCP’nin kullanımının tanısal değeri olduğu sonucuna varılabilir.

Anahtar Kelimeler:

Vücut kompozisyonu, bioimpedans analizör, nonalkolik yağlı karaciğer hastalığı, obezite

The association of body composition parameters with nonalcoholic hepatic steatosis

Objective: Nonalcoholic fatty liver disease (NAFLD) which is strongly correlated with obesity; has been a common worldwide health problem with the improvements in social status. Body composition studies are accepted as a simple follow-up tool for treatment of obesity. Since the correlation of body mass index (BMI) with the hepatosteatosis (HS) is well known; the aim of this study was to assess the usefulness of body composition parameters (BCP) to determine HS on NAFLD patients; using dual bioimpedance analyzer (BIA).Methods: A total of 253 patients with diagnosis of NAFLD were included into the study. The demographic parameters such as age, sex and BMI were collected; and the ultrasonographic (US) evolution was performed to determine the HS stages. The BCP, such as amount and the percentage of total body fat, fat free mass, and total body water were assessed with the dual bioimpedance analyzer.Results: There were strong significant correlations between BMI and HS, between BCP and HS (p<0.05). However, no statistically significant superiority of BCP was found when compared with BMI regarding diagnostic value for NAFLD (p>0.05).Conclusion: According to our results, it can be concluded that BCP values may have a diagnostic value on diagnosis of NAFLD.

Keywords:

Body composition, bioimpedance analyzer, nonalcoholic fatty liver disease, obesity,

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