Mustafa TAŞKESEN, Selahattin KATAR, Sultan ECER, Mehmet KERVANCIOĞLU, Şeyhmus SEVİNC

Typhoid fever complicated by multiple organ ınvolvement in a child

12 yaşında kız çocuğu kliniğimize 10 günden beridir olan ateş, baş ağrısı, ishal ve halsizlik nedeni ile başvurdu. Fizik muayenede taşikardi, dispne, hipotansiyon, ateş ve uyku hali tespit edildi. Laboratuvar incelemede üre, kreatinin, aspartat ve alanin aminotransferaz düzeyleri yükselmiş bulundu. Ekokardiografik değerlendirmede sistolik fonksiyonlar azalmış ve miyokardiyal disfonksiyon belirlendi. Kan kültüründe S.typhi üredi. Enterik ateşli bir hastada çoklu organ tutulumunu literatür eşliğinde sunmayı amaçladık.

Bir çocukta multiorgan tutulumu gösteren tifo ateşi

A 12-year old girl was admitted to our clinic because of fever, headache, diarrhea and weakness for 10 days. Dyspne, tachycardia, hypotension, fever and letargy were determined in physical examination. The levels of urea, creatinine, aspartate aminotransferase, alanine aminotransferase were found to be increased. In echocardiography, myocardial dysfunction and low systolic functions were detected. Blood culture was positive for S.typhi. We report multiple organ involvement in a patient with typhoid fever and review the literature

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1. Noguera MA, Cleary OG, Cleary TG. Typhoid fever. In: Burg FD, Ingelfinger JR, Polin RA, Gershon AA. Gellis and Kagan’s Current Pediatric Therapy Philadelphia WB Saunders Company 2002;111-12.
2. Shetty AK, Mital SR, Bahrainwala AHT, Khubchandani RP, Kumta NB. Typhoid hepatitis in children. Journal of Tropical Pediatrics 1999;45:287-90.
3. Simpson J, Watson AR, Mellersh A, Nelson CS, Dodd K. Typhoid fever, ciprofloxacin and renal failure. Archieve Dis Child 1991;66:1083-84.
4. Diem LV, Arnold K. Typhoid fever with myocarditis. America J Trop Med Hyg 1974; 23:213-21.
5. Ozen H, Seçmeer, Kanra G et al. Typhoid fever with very high transaminase levels. Turkish J Pediatr 1995;37: 169-71.
6. Yaramis A, Yildirim I, Katar S, et al. Clinical and laboratory presentation of typhoid fever. International Pediatrics 2001; 16:227-31.
7. Katar S, Onur H, Yaramis A, Ozbek MN, Ecer S. Çocuklarda kültür pozitif enterik ateş. Çocuk Sağlığı ve Hastalıkları Dergisi 2006;49: 19-23.
8. Secmeer G, Kanra G, Cemeroglu AP, et al. Salmonella typhi infections. A 10-years retrospective study. Turk J Pediatrics 1995;37:339-41.
9. Fyler CD. Pericardial disease. In: Nadas’ Pediatric Cardiology. Philadelphia: Hanley Belfus, 1992; 363-368.
10. Baysal K, Sancak R, Ozturk F, Uysal S, Gurses N. Cardiac involvement due to Salmonella typhi infections in children. Annals of Trop Paediatr 1998;18:23-25.
11. Aka S, Kıral A, Sümer M, Yavrucu S, Karatoprak N, Ozguner A. Enterik ateş tanısı ile izlediğimiz olgularımızın retrospektif incelenmesi. Türk Pediatri Arşivi 2001;36:79-83.
12. Kuchar E, Kacprzak IB. Typhoid fever in a child- a case report. Przegl Epidemiology 2004;58(1):213-218.
13. Faierman D, Ross FA, Seckler SG. Typhoid fever complicated by hepatitis, nephritis, and thrombocytopenia. JAMA 1972; 221:60–61.
14. Hayashi M, Kouzu H, Nishihara M, et al. Acute renal failure likely due to acute nephritic syndrome associated with typhoid fever. Int Medicine 2005;44:1074-77.