Terapötik gazlar: Oksijen, karbondioksit, nitrik oksid ve helyum

Bu derlemede sık kullanılan terapötik gazlardan olan Oksijen, Karbondioksit, Nitrik oksid ve Helyumun yapıları, fizyolojik etkileri, toksisiteleri, kullanım metodları ve endikasyonları sunulmuştur.
Anahtar Kelimeler:

Nitrik oksit, Karbon dioksit, Helyum, Oksijen

Therapeutic gases: Oxygen, carbondiokside, nitric oxide and helium

This review is about the structures of commonly used therapeutic gases Oxygen, Carbondiokside, Nitric Oxide and Helium. Their structures, effects on physiological systems, toxicities, usage indications and methods are presented.

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  • 1. Clark JM. Pulmonary limits of oxygen tolerence in man. Exp. Lung Res. 1988; 14:897-910.
  • 2. Nunn JF. Hypoxia. In, Nunn’s Applied Respiratory Physiology, 4th ed. (Nunn, JF., ed.) Butterworth-Heineman, Oxford, 1993; 535-536.
  • 3. McCord JM. Oxygen-derived free radicals in postischemic tissue injury . N. Engl.J. Med. 1985; 312:159-163.
  • 4. Cruz JC, Reeves JT, Grover RF, et all. Ventilatory acclimatization to high altitude is prevented by CO2 breathing. Respiration 1980; 39:121-130.
  • 5. Grover RF, Vogel JH, Voigt GC and Blount SG Jr. Reversal of high altitude pulmonary hypertension. Am. J. Cardiol. 1966; 18:928-932.
  • 6. Benatar SR, Hewlett AM, and Nunn JF. The use of iso-shunt lines for control of oxygen therapy. Br. J. Anaesth. 1973; 45:711- 718.
  • 7. Coursin DB, Cihla, HP, Will JA, and McCreary JL. Adaptation to chronic hyperoxia. Biochemical effects and the response to subsequent lethal hyperoxia. Am. Rev. Respir. Dis. 1987; 135:1002-1006.
  • 8. McCord JM. Oxygen-derived free radicals in postischemic tissue injury. N. Engl. J. Med. 1985; 312:159-163.
  • and Crystal RG. Pulmonary oxygen toxicity. Early reversibl changes in human alveolar structures induced by hyperoxia. N. Engl. J. Med. 1983; 309:878-883.
  • 10. Nattie E. CO2 brainstem chemoreceptors and breathing. Prog. Neurobiol. 1999; 59:299-331.
  • 11. Staszewska-Barczak J and Dusting GJ. Importance of circulating angiotensin II for elevation of arterial pressure during acute hypercapnia in anesthetised dogs. Clin. Axp. Pharmacol. Physiol. 1981; 8:189-201.
  • 12. Goodman and Gilman’s The Pharmacological Basis of Therapeutics Tenth Edition 2002: 395-396.
  • 13. Van den Bos GC, Drake AJ, and Noble MIM. The effect of carbon dioxide upon myocardial contractile performance, blood flow and oxygen consumption. J. Physiol. (Lond.) 1979; 287:149-161.
  • 14. Ely SW, Sawyer DC ve Scott JB. Local vasoactivity of oxygene and carbondiokside in the right coronary circulation of the dog and pig. J. Physiol. (lond.) 1982; 332:427-439.
  • 15. Duane SF, Weir EK, Stewart RM and Niewoehner DE. Distal airway responses to changes in oxygene and carbondiokside tensions. Respir. Physiol. 1979; 38:303-311.
  • 16. Moncada S, Palmer RM, Higgs EA. Nitric oxide: physiology, pathophysiology, and pharmacology.Pharmacol Rev. 1991; 43:109- 142.
  • 17. Nathan C. Nitric oxide as a secretory product of mammalian cells. FASEB J. 1992;6:3051-3064.
  • 18. Ignarro LJ, Cirino G, Casini A, Napoli C. Nitric oxide as a signaling molecule in the vascular system: an overview.J Cardiovasc Pharmacol. 1999;34:879-886.
  • 19. Wass C, Archer T, Palsson E, et all. Effects of phencyclidine on spatial learning and memory: Nitric oxide-dependent mechanisms.Behav Brain Res. 2006; issue 1:147- 153.
  • 20. Toda N, Herman AG. Gastrointestinal function regulation by nitrergic efferent nerves. Pharmacol Rev. 2005; Sep;57:315-338.
  • 21. Araujo M, Welch WJ. Oxidative stress and nitric oxide in kidney function. Curr Opin Nephrol Hypertens. 2006; Jan;15:72- 77.
  • 22. Bronte V, Zanovello P. Regulation of immune responses by L-arginine metabolism.Nat Rev Immunol. 2005; 5:641-654.
  • 23. Roberts JD Jr, Fineman JR, Morin FC III, et all. Inhaled nitric oxide and persistent pulmonary hypertension of the newborn. The inhaled Nitric Oxide Study Group. N.Engl. J. Med. 1997; 336:605-610.
  • 24. Cheung PY, Salas E, Schulz R, Radomski MW. Nitric oxide and platelet function: implications for neonatology.Semin Perinatol. 1997; 21:409-417.
  • 25. Rassaf T, Kleinbongard P, Kelm M.Circulating NO pool in humans.Kidney Blood Press Res. 2005;28:341-348.
  • 26. Steudel W, Hurford WE, Zapol WM. Inhaled nitric oxide: basic biology and clinical applications.Anesthesiology 1999; 91:1090- 1121.
  • 27. Greenough A, Khetriwal B. Pulmonary hypertension in the newborn. Paediatr. Respir. Rev. 2005; 6:111-116.
  • 28. Manukhina EB, Downey HF, Mallet RT. Role of nitric oxide in cardiovascular adaptation to intermittent hypoxia.Exp Biol Med (Maywood). 2006; 231:343-365.
  • 29. Schoen Smith JM, Lautt WW. Nitric oxide and prostaglandins potentiate the liver regeneration cascade.Can J Gastroenterol. 2006; 20:329-334.
  • 30. Choi J, Hoffman LA, Rodway GW, Sethi JM. Markers of lung disease in exhaled breath: nitric oxide. Biol Res Nurs. 2006; 7:241- 255.
  • 31. Cheifetz IM. Inhaled nitric oxide: plenty of data, no consensus. Crit. Care Med.2000; 28:902-903.
  • 32. Barach A. The use of helium in the treatment of asthma and obstructive lesions in the larynx and trachea. Ann Intern Med. 1935; 9:739–765.
  • 33. Shiue MD, Gluck EH. The use of helium-oxygen mixtures in the support of patients with status asthmaticus and respiratory acidosis. J Asthma 1989; 26:177–180.
  • 34. Rodrigo G, Rodrigo C, Pollack C, et al. Helium-oxygen mixtures for non-intubated acute asthma patients. Cochrane Library. Issue 4. Oxford: Update Software, 2001.
  • 35. McGee DL, Wald DA, Hinchcliffe S. Helium-oxygen therapy in the emergency department. J Emerg Med. 1997; 15:291–296.
  • 36. Browne-Heitschmidt MG, Cassidy JB. Heliox: a new treatment for life-threatening asthma. Pediatric Nursing 1997; 23:479–482.
  • 37. Madison JM, Irwin RS. Heliox for asthma, a trial balloon. Chest 1995; 107:597– 598.
  • 38. Ball JAS, Rhodes A, Grounds RM. A review of the use of helium in the treatment of acute respiratory failure. Clinical Intensive Care 2001; 12:105–113.
  • 39. Thoracic Society. British guideline in the management of asthma. Thorax 2003; 58(suppl 1) i1-94.
  • 40. Manthous CA, Morgan S, Pohlman A. Heliox in the treatment of airflow obstruction: a critical review of the literature. Resp Care 1997; 42:1034–1042.
  • 41. Sidwa DM, Montenegro HD, Goldman MD, et al. Helium-oxygen breathing in severe chronic obstructive pulmonary disease. Chest 1985; 87:790–795.
  • 42. Bechler-Karsch A. Assessment and management of status asthmaticus. Pediatric Nursing 1994; 20:217–223.
  • 43. Austan F. Heliox inhalation in status asthmaticus and respiratory acidaemia: a brief report. Heart Lung 1996; 25:155–157.