Psöriazis vulgaris hastalarında nötrofil/lenfosit oranı, trombosit/lenfosit oranı, ortalama trombosit hacmi ve C-reaktif protein değerleri

Amaç: Son yıllarda nötrofil/lenfosit oranı (NLO), trombosit/lenfosit oranı (TLO),ortalama trombosit hacmi(OTH) ve C reaktif protein(CRP)’nin sistemik inflamasyonun önemli göstergeleri olduğu gösterilmiştir. Yapılan çalışmalarda psöriazis vulgaris hastalarında NLO, TLO, OTH ve CRP ’nin kontrol gurubuna göre daha yüksek olduğu gösterilmiştir. Çalışmamızda psöriazisli hastaların NLO, TLO, OTH ve CRP düzeyleri ölçüldü ve bu parametrelerin tırnak tutulumu, artrit varlığı, hastalık süresi ve PAŞİ skoru ile ilişkili olup olmadığı araştırıldı. Yöntemler: Herhangi bir sistemik hastalığı, infeksiyöz hastalığı ve otoimmun hastalığı olmayan 133 psöriazis vulgaris hastası ve 107 sağlıklı kontrol çalışmaya dahil edildi. Hastalar PAŞİ skoruna göre hafif (PAŞİ

Evaluation of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, mean platelet volume, and C-reactive protein in patients with psoriasis vulgaris

Objective: Recent reports indicate that neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), mean platelet volume (MPV), and C-reactive protein (CRP) are key markers of systemic inflammation. These markers have also been shown to be significantly increased in patients with psoriasis vulgaris compared to control subjects. In this study, we aimed to evaluate the relationship between serum levels of NLR, PLR, MPV, and CRP and nail involvement, presence of arthritis, duration of disease, and Psoriasis Area and Severity Index (PASI) scores in patients with psoriasis vulgaris. Methods: The study included 133 patients with psoriasis vulgaris that had no systemic, infectious, or autoimmune diseases and a control group of 107 healthy volunteers. The patients were divided into two groups based on their PASI scores: (I) mild (PASI

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