Postmortem biyokimya

Postmortem biyokimya son yıllarda hızla adli patoloji alanında rutin kullanıma girmeye ve bu alanda giderek önem kazanmaya başlamıştır. Rutin uygulanan ful otopsi içinde biyokimyasal incelemelerin de yer alması; ölüm öncesi var olan akut/kronik patolojileri, ölüme sebep olabilecek hastalıkları, ölüm sürecinde kişinin metabolik durumunu, canlılık süresini, ölüm sonrası biyokimyasal değişiklikleri ve analitlerin kaynağını göstermesi açısından önemli bilgiler sağlayabilir. Özellikle klasik otopsi ile yapılan morfolojik incelemelerin yetersiz kaldığı durumlarda (Diabetes Mellitus (DM), alkolik ketoasidoz, sepsis, elektrolit bozuklukları) biyokimyasal tetkikler çok değerli olabilir. Bu yazıda literatür araştırmasına dayalı postmortem biyokimya ile ilgili yapılmış çalışmalara atıfta bulunarak otopsi incelemelerinde başvurulabilecek biyokimyasal analitler üzerinde kısaca durulmuştur.

Postmortem biochemistry

Postmortem biochemistry is becoming more important in forensic pathology. Involving of biochemical investigations full autopsy can provide to detect divers pathologic conditions such as antemortem acute/chronic diseases, fatal metabolic conditions, survival time, postmortem biochemical changes, and the source of analytes. Biochemical tests may be usefull where the morphological examinations cannot lighten the fatal pathology (Diabetes Mellitus (DM), alcoholic ketoacidosis, sepsis, electrolytic disorders). This article presents the analytes that may be useful in forensic medicine upon the studies performed and published in the literature.

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