Non-Valvüler Atriyal Fibrilasyon Hastalığı Olan Bireylerde Cha2ds2-Vasc –Skorunun Ekokardiyografik Parametrelerle İlişkisi: Tek Deneyim Merkezi

Amaç: Atriyal fibrilasyon (AF) nın tromboembolik olaylarından korunmak için Oral-antikoagülan (OAK) başlama endikasyonu CHA2DS2VASc puanlama sisteminde iki ve üzeri olan bireylerde OAK kullanımı tavsiye edilmektedir. Non-valvüler AF hastalarının tedavisinde oral antikoagülan kullanım endikasyonu belirlenmesinde CHA2DS2-VASc skorunun kullanılması ile beraber ekokardiyografik (Epikardiyal yağ dokusu(EYD) karotis intima media kalınlığının (KİMK) (aortik propagasyon velositesi) AVP) parametreler non-valvüler AF'nin tedavisi için önemli bir hedef organı olabilir. Yöntemler: Non-valvüler atriyal fibrilasyon tanısı alan ve 18-90 yaş aralığında başvuran 100 hasta üzerinden gerçekleştirilmiştir. Kontrol grubu için çalışmaya dahil edilen 50 hasta ile birlikte çalışmada toplam 150 birey gözlemlenmiştir. Hastalara ait AVP, EYD, KİMK değerleri ekokardiografi laboratuvarımızdaki VividE9 Ekoakardiyografi cihazı (Advenced Technology Laboratories) kullanılarak 3.0 ve 10-MHz’lik problar ile gerçekleştirildi. Bulgular: Bizim çalışmamamızın verileri sonucunda Epikardiyal yağ dokusu ve karotis intima media kalınlığı CHA2DS2-VASc skoruyla ilişkisi istatiksel olarak anlamlı bulundu ,Aortik Propagasyon Velositesi ile anlamlı bulunmadı. Çalışmamızda hasta sayımızın azlığı,çok fazla kişisel ve/veya işlemsel farklılık saptanmasınında payı olabileceğinden dolayı bu konuda daha fazla hasta sayısını içeren prospektif çalışmaların yapılmasına ihtiyaç vardır. Sonuç. Non-valvüler AF hastalarının tedavisinde oral antikoagülan kullanım endikasyonu belirlenmesinde CHA2DS2-VASc skorunun kullanılması ile beraber ekokardiyografik (AVP, EYD, KİMK) parametreler non-valvüler AF'nin tedavisi için önemli bir hedef organı olabilir.

Anahtar Kelimeler:

Non-valvüler atriyal fibrilasyon, CHA2DS2-VASc skoru, karotis intima media kalınlığı, aortik propagasyon velositesi, epikardial yağ dokusu

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