DOWN SENDROMLU ÇOCUKLARDA UYKU APNE SENDROMU VE AĞIZ DİŞ SAĞLIĞI

Down Sendromu (DS) (Trizomi 21) yeni doğanın mental ve fiziksel retardasyonunu içeren yaygın kromozom anomalilerinden biridir. Down Sendrom’lu bireylerde; birçok sağlık sorunu doğrudan veya dolaylı olarak meydana gelmekte, hastanın hayat kalitesini ve yaşam süresini etkilemektedir. Bu hastalıklardan bazıları önemli boyutta medikal takip gerektirmektedir. Down Sendrom’lu çocuklarda Obstruktif Uyku Apne Sendromu önemli sağlık problemlerinden biridir. Sağlıklı çocuklarda Obstruktif Uyku Apne Sendromu görülme prevelansı % 0,7-2 arasında değişirken, Down Sendrom’lu çocuklarda bu oran % 31-75’lere kadar yükselmektedir Obstruktif Uyku Apne Sendromu tanısı koyulurken altın standart teşhis yöntemi uyku sırasında polisomnografi uygulamasıdır. Obstruktif Uyku Apne Sendromu’nun, Down Sendrom’lu pediatrik hasta grubunda ağız diş sağlığını nasıl etkilediğine yönelik derinlemesine çalışmalara ihtiyaç duyulmaktadır. Anahtar Kelimeler: Down Sendromu, Obstruktif Uyku Apnes Down Sendromu (DS) (Trizomi 21) yeni doğanın mental ve fiziksel retardasyonunu içeren yaygın kromozom anomalilerinden biridir. Down Sendrom’lu bireylerde; birçok sağlık sorunu doğrudan veya dolaylı olarak meydana gelmekte, hastanın hayat kalitesini ve yaşam süresini etkilemektedir. Bu hastalıklardan bazıları önemli boyutta medikal takip gerektirmektedir. Down Sendrom’lu çocuklarda Obstruktif Uyku Apne Sendromu önemli sağlık problemlerinden biridir. Sağlıklı çocuklarda Obstruktif Uyku Apne Sendromu görülme prevelansı % 0,7-2 arasında değişirken, Down Sendrom’lu çocuklarda bu oran % 31-75’lere kadar yükselmektedir Obstruktif Uyku Apne Sendromu tanısı koyulurken altın standart teşhis yöntemi uyku sırasında polisomnografi uygulamasıdır. Obstruktif Uyku Apne Sendromu’nun, Down Sendrom’lu pediatrik hasta grubunda ağız diş sağlığını nasıl etkilediğine yönelik derinlemesine çalışmalara ihtiyaç duyulmaktadır.Anahtar Kelimeler: Down Sendromu, Obstruktif Uyku Apnesi OBSTRUCTIVE SLEEP APNEA AND ORAL HEALTH IN CHILDREN WITH DOWN SYNDROMEABSTRACT Down syndrome is the most common chromosomal disorder in newborns and causes delays in physical and intellectual development. Children with Down syndrome are at an increased risk for health complications beyond usual childhood illnesses and are at high risk for many disorders known to interfere with growth requring medical follow up whole life. Obstructive Sleep Apnea is one of the major health problem in children with Down Syndrome. Among the general pediatric population, up to 2-4% of children experience Obstructive Sleep Apnea. Children with Down Syndrome are at an increased risk for Obstructive Sleep Apnea when compared to children without Down Syndrome, with reported prevalence rates of 31±75% among clinic-based samples. The gold standard for diagnosis of Obstructive Sleep Apnea is overnight polysomnogrphy. Furthermore studies should be done to clarify how Obstructive Sleep Apnea affects oral health in children with Down Syndrome.Key Words: Down’s Syndrome, Obstructive Sleep Apnea i

Anahtar Kelimeler:

Down Sendromu

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