Gülcan ÜNSAL, Özge ÖZMEKİK, İşın ULUKAPI

DENTAL KÖK HÜCRELER VE SÜT DİŞLERİNİN KÖK HÜCRE ÇALIŞMALARINDAKİ ÖNEMİ

Kök hücreler sınırsız bölünebilme ve kendini yenileme özelliğine sahip, vücudumuzda doku ve organları oluşturan ana hücrelerdir. Kolay ulaşılabilmeleri ve minimal invaziv işlem gerektirmeleri nedeni ile dental kök hücreler postnatal kök hücre kaynakları arasında yerini almıştır. Dental pulpada, apikal papillada, periodontal ligamentte, dental folikülde ve süt dişinde multipotent kök hücreler izole edilmiştir. Düşen süt dişi kök hücrelerinin nöronlara, adipozitlere, kondrositlere, osteoblastlara ve odontoblastlara diferansiye olduğu tespit edilmiş, otolog kök hücre tabanlı tedavilerde alternatif kök hücre kaynağı oluşturabileceği bildirilmiştir.

Anahtar Kelimeler:

Kök Hücre, süt dişi, mezenkim, multipotent

DENTAL STEM CELLS AND THE IMPORTANCE OF DECIDIOUS TEETH FOR STEM CELL STUDIES

Stem cells are fundemental cells that have charecteristics of self-renewal and being divided unlimitedly, and generate tissue and organs. Dental stem cells have taken place among the postnatal stem cell sources as they are easy to get and require minimally invasive process. Multipotent stem cells in dental pulp, apical papilla, periodontal ligament, dental follicle and decidious teeth are isolated. It is determined that stem cells from human exfoliated decidious teeth differantiate to neurons, adipocytes, chondrocytes, osteoblasts and odontoblasts, and it is reported that they can be alternative stem cell source at autolog stem cell based therapy

Keywords:

Stem cell, decidious teeth, mesenchyme, multipotent,

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