Yrd. Doç. Dr. Kamile ERCİYAS, Yrd. Doç. Dr. Kemal ÜSTÜN, Dr. Yavuz PEHLİVAN, Doç. Dr. Ahmet Mesut ONAT
ANKİLOZAN SPONDİLİT VE PERİODONTAL SAĞLIK: BİR PİLOT ÇALIŞMA
Amaç: Periodontal hastalıklar dişi destekleyen dokuların kaybı ile karakterize bir enfeksiyondur. Dental plak mikroorganizmalarına karşı yerel ve sistemik konak cevabının oluşması nedeniyle bu enfeksiyonun genel sağlığı ve bazı sistemik hastalıkların seyrini etkileyebileceği düşünülmektedir. Bu çalışmanın amacı ankilozan spondilitli bireylerin ağız sağlığını ve periodontal durumunu sistemik ve periodontal açıdan sağlıklı bireylerle karşılaştırmaktır. Gereç ve yöntem: Çalışmaya Ankikozan spondilit teşhisi konulmuş 35 birey ve 36 sağlıklı kontrol grubu dahil edildi. Hastalar hem klinik hem de radyografik olarak değerlendirildi. Tüm bireylerde gingival indeks, plak indeksi, sondalabilen cep derinliği ölçümü, klinik ataşman düzeyi ve eksik diş sayısı kaydedildi. Bulgular: İstatistiksel analizler sonucunda tüm periodontal parametreler ankilozan spondilit grubunda kontrol grubuna göre anlamlı derecede yüksek bulundu. Sonuç: Ankilozan spondilit hastalığı bulunan bireylerin ağız ve periodontal sağlığının iyi olmadığı belirlenmiştir. Hasta grubumuzun periodontitisin oluşturduğu sistemik etkilerin ankilozan spondilitin sistemik bulgularını etkileme riskinden korunabilmeleri için periodontal sağlıklarına önem vermeleri gereklidir.
Anahtar Kelimeler:
Ankilozan spondilit, periodontitis, gingivitis
ANKYLOSING SPONDYLITIS AND PERIODONTAL HEALTH: A PILOT STUDY
Objective: Periodontal diseases are characterized with inflammation in periodontal supportive tissues and alveolar bone resorbtion. They might interfere with systemic health or systemic disease pattern via local and systemic host response occurred against bacteria. The aim of this study is to compare the oral and periodontal health status of ankylosing spondylitis and healthy control groups. Material and Methods: In this study were included in 35 subjects with rheumatoid arthritis and 36 healthy controls. Patients were evaluated as both clinical and radio graphical. The measurement of gingival index, plaque index, probing depth, clinical attachment levels and the number of missing teeth were recorded. Results: After the statistical analyses, all of the clinical periodontal parameters were found significantly higher in ankylosing spondylitis group than the control group. Conclusion: The results of this study showed weak oral health and periodontal status in patients with ankylosing spondylitis. The individuals with ankylosing spondylitis should intensively take care about their periodontal health to prevent from the risk of periodontitis development, and the systemic effects of periodontitis on the systemic symptoms of ankylosing spondylitis.
Keywords:
Ankylosing spondylitis, periodontitis, gingivitis,
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- Sorenson LK, Havemose-Poulsen A, Sonder SU, Bendtzen K, and Holmstrup P. Blood cell gene expression profiling in subjects with aggressive periodontitis and chronic arthritis. J Periodontol. 2008; 79: 477-485.
- Han C, Robinson DWJ, Hackett MV, Paramore LC, Fraeman KH, Bala MV. Cardiovascular disease and risk factors in patients with rheumatoid arthritis, psoriatic arthritis, and ankylosing spondilytis. J Reumatol. 2006; 33: 2167-2172.
- Tüter G, Aykan T, Kurtiş B, Toyman U, Pınar S, Okyay K. Evaluation of the oral health status in patients with coronary artery disease. Türkiye Klinikleri J Dental Sci. 2008; 14: 85-90.
- Taylor GW. Bidirectional interrelationships between diabetes and periodontal diseases: an epidemiologic 2001;6: 99-112. Ann Periodontol.
- Brown DL, Desai KK, Vakili BA, Nouneh C, Lee HM, Golub LM. Clinical and biochemical results of the antimicrobial doses of doxycycline to prevent inhibition with sub- acute coronary syndromes (MIDAS) pilot trial. Arterioscler Thromb Vasc Biol. 2004; 24: 733-738.
- Brennan RM, Genco RJ, Hovey KM, Trevisan M, Wactawski-Wende J. Clinical attachment loss, systemic bone density, and subgingival calculus in postmenopausal women. J Periodontol. 2007; 78(11):2104-2111.
- Van Doornum S, McColl G, Wicks IP. Accelerated atherosclerosis: an extraarticular feature of rheumatoid arthritis? Arthritis Rheum. 2002; 46: 862–873.
- Nilsson M, Kopp S. Gingivitis and periodontitis are related to repeated high levels of circulating tumor necrosis factor-alpha in patients with rheumatoid arthritis. J Periodontol. 2008; 79: 1689-1696.
- Pishon N, Pishon T, Kröger J, Gülmez E, Kleber BM, Bernimounlin JP, Landau H, Brinkmann PG, Schlattmann P, Zernicke J, Bruttgereit F, and Detert J. Association among rheumatoid arthritis, oral hygiene, and periodontitis. J Periodontol. 2008;79: 979-986.
- Al-Katma MK, Bissada NF, Bordeaux JM, Sue J, Askari AD. Control of periodontal infection reduces the severity of active rheumatoid arthritis. J Clin Rheumatol. 2007; 13: 134-137.
- Bartold PM, Marshall RI, Haynes DR. Periodontitis and rheumatoid arthritis: a review. J Periodontol. 2005; 76: 2066-2074.
- Pishon N, Pishon T, Gülmez E, Kröger J, Purucker P, Kleber BM, Landau H, Jost-Brinkmann PG, Schlattmann P, Zernicke J, Burmester G, Bernimounlin JP, Bruttgereit F, and Detert J. Periodontal disease in patients with ankylosing spondylitis. doi:10.1136/ard.2008.097212. Rheum. 2009;
- Sari I, Okan T, Akar S, Cece H, Altay C, Secil M, Birlik M, Onen F, and Akkoc N. Impaired endothelial function in patients with ankylosing spondylitis. Rheumatology. 2006; 45: 283–286.
- Löe H, Silness J. Periodontal disease in pregnancy I. Prevalence and severity. Acta Odont Scand. 1963; 21: 533-551.
- Silness J, Löe H. Periodontal disease in pregnancy. II. Correlation between oral hygiene and periodontal condition. Acta Odont Scand. 1964; 22: 121-135.
- Mercado F, Marshall RI, Klestov AC, Bartold PM. Is there a relationship between rheumatoid arthritis and periodontal disease? J Clin Periodontol. 2000; 27: 267-272.
- Bıyıkoğlu B, Buduneli N, Kardeşler L, Aksu K, Öder G, Kütükçüler N. Evaluation of t-PA, PA-2, IL-1a, and PGE2 in gingival crevicular fluid of rheumatoid arthritis patients with periodontal disease. J Clin Periodontol. 2006; 33: 605-611.
- Bozkurt FY, Yetkin Ay Z, Berker E, Tepe E, Akkus S. Anti-inflammatory Cytokines in Gingival Crevicular Fluid in Patients with Periodontitis and Rheumatoid Arthritis: a preliminary report. Cytokine. 2006; 35: 180-185.
- Bozkurt FY, Berker E, Akkuş S, Bulut Ş. Relationship between IL-6 levels in gingival crevicular fluid and periodontal status in patients with rheumatoid arthritis and adult periodontitis. J Periodontol. 2000; 71: 1756-1760.
- Sjöström L, Laurell L, Hugoson A, Hakansson JP. Periodontal conditions in adults with rheumatoid arthritis. Community Dent Oral Epidemiol. 1989; 17: 234-236.
- Helenius LM, Meurman JH, Helenius I, Kari K, Hietanen J, Suuronen R, Hallikainen D, Kautiainen H, Leirisalo-Repo M, Lindgvist C. Oral and salivary parameters in patients with rheumatic diseases. Acta Odontol Scand. 2005; 63(5):284-293.
- Tüter G, Aykan T, Kurtiş B, Toyman U, Pınar S, Okyay K. Evaluation of the oral health status in patients with coronary artery disease. Türkiye Klinikleri J Dental Sci. 2008; 14: 85-90.
- Başlangıç: 1986
- Yayıncı: Atatürk Üniversitesi
Sayıdaki Diğer Makaleler
YEDİNCİ JENERASYON ADEZİV SİSTEMLERİNİN DENTİNE MAKASLAMA BAĞLANMA DAYANIMLARININ KARŞILAŞTIRILMASI
Prof. Dr. Abdülkadir ŞENGÜN, Yrd. Doç. Dr. Muhammet YALÇIN, Dt. Ayşe KOCABAŞOĞLU
ANKİLOZAN SPONDİLİT VE PERİODONTAL SAĞLIK: BİR PİLOT ÇALIŞMA
Yrd. Doç. Dr. Kamile ERCİYAS, Yrd. Doç. Dr. Kemal ÜSTÜN, Dr. Yavuz PEHLİVAN, Doç. Dr. Ahmet Mesut ONAT