Necmettin AKDENİZ, Akın AKTAŞ, Okan KIZILYEL, Mahmut Sami METİN, Handan BİLEN, Ömer Faruk ELMAS, Mustafa ATASOY

Pyogenic granuloma-like Kaposi sar- coma: Report of two cases

Kaposi sarkomu Human Herpes Virüsü-8 enfeksiyonu ile ilişkili vasküler bir tümördür. Lezyonlargenellikle mukokutanöz bölgelere yerleşir. Ancak tüm organlarda görülebilir. Kaposi sarkomununbirçok varyantı vardır. Piyojenik granülom benzeri Kaposi sarkomu deriden kabarık olan vepiyojenik granüloma benzeyen yeni bir varyanttır. Literatürde, piyojenik granülom benzeri Kaposisarkomu ile ilgili sadece birkaç olgu sunulduğu ve genellikle piyojenik granülom yanlış tanısıaldığı için Kaposi sarkomlu iki olguyu sunmaya karar verdik.

Piyojenik granülom benzeri Kaposi sarkomu: İki olgu sunumu

Kaposi sarcoma is a vascular tumor associated with Human Herpes Virus-8 infections. Lesionspredominantly present at mucocutaneous sites but may involve all organs. There are many kinds ofKaposi sarcoma variants. Pyogenic granuloma like Kaposi sarcoma is a new variant whichprotrudes from skin and resembles a pyogenic granuloma. We decided to report two cases ofKaposi sarcoma because there are only few case reports about pyogenic granuloma like Kaposisarcoma in literature, which is usually misdiagnosed as pyogenic granuloma.

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1. Radu O, Pantanowitz L. Kaposi Sarcoma Review, Arch Pathol Lab Med 2013; 137: 289-94.
2. Kaposi M. Idiopathisces multiples Pigmentsarkom der Haut. Archiv fur Dermatologi und Syphilis 1872; 3: 265-73.
3. Chang Y, Cesarman E, Pessin MS. Identification of herpesvirus-like DNA sequences in AIDS- associated Kaposis sarcoma. Science 1994; 266: 1865-9.
4. Antman K, Chang Y. Kaposiis sarcoma. N Engl J Med 2000; 342: 1027-38.
5. Hbid O, Belloul L, Fajali N, Ismai- li N, Duprez R, Tanguy M, Be- nomar H, Tahri EH, Gessain A, Huerre M. Kaposiis sarcoma in Morocco: A pathological study with immunostaining for human herpesvirus-8 LNA-1. Pathology 2005; 37: 288-95.
6. Grayson W, Pantanowitz L. Histological variants of cutaneous Ka- posi sarcoma review, Diagnostic Pathology 2008; 3: 31.
7. Wyatt M, Finlayson C, Gillon M. Kaposis sarcoma masquerading as pyogenic granuloma of the nasal mucosa. The Journal of Laryngol- ogy and Otology 1998; 112: 280-2.
8. Fukunaga M. Kaposis sarcoma like pyogenic granuloma. Histopathology 2000; 37: 192-3.
9. Scott P, Motaparthi K, Krishnan B, Hsu S. Pyogenic granuloma like Kaposi sarcoma: A diagnostic pit- fall. Dermatology Online Journal 2012; 18: 3.
10. Ryan P, Aarons S, Markham T, Sullivan S, Lyons F, Lee G, Fitz- gibbon J. HHV8 detected in two patients with Kaposis sarcoma like pyogenic granuloma. J.Clin Pathol 2002; 55: 619-22.
11. Cheuk W, Wong K, Wong C, Dinkel J, Dor D, Chan J. Im- munostaining for HHV8 LNA-1 helps distinguish Kaposi Sarcoma from its mimickers. Am J Clin Pathol 2004; 121: 335-42.