Fatih AYGÜN, Türker ACAR, Melda YILDIZ, Duran EFE, Kazım GEMİCİ

Investigation of the relationship between Abdominal Aortic Calcified Plaques deter- mined by multidetector computed tomogra- phy (MDCT) and Body Mass Index (BMI)

Amaç: Bu çalışmada, multidedektörlü BT (MDBT) ile ölçülmüş abdominal aort aterosklerozu vevücut kitle indeksi arasında olası ilişki araştırıldı.Yöntem: Çalışmamız kliniğimizde temmuz 2013 ve ocak 2014 tarihleri arasında kontrassızabdominal BT çekilen 228 kişiyi içermektedir. BT aksiyel kesitlerde çöliyak trunkus ve iliakbifurkasyon arasında abdominal aort kalsifik plaklarının kalsiyum skorları (AaCs) Agatston üniti(a.u) olarak ölçüldü Tüm hastalarımızın abdominal BT çekim sonrasında, boy (İnsan baskülü,NAN TARTI AŞ, Türkiye) ve kiloları (TANITA Body Composition Analyzer, TANITACorporation, Japan) ölçüldü. Vücut kitle indeksleri hesaplandı. BMIi 25 kilogram (kg)/metrekare(m2) nin altında olanlar (BMI

Abdominal Aort Kalsifik plak oluşumu ile Vücut Kitle İndeksi arasındaki ilişkinin MDCT ile araştırılması

Objective: Potential correlation between abdominal aortic atherosclerosis measured bymultidetector computed tomography (MDCT) and body mass index (BMI) is investigated in thispresented study.Method: The presented study includes 228 patients between July 2013 and January 2014 in ourclinic. Calcium scores of abdominal aortic calcified plaques (AaCs) between celiac trunk and iliacbifurcation in axial sections were measured as Agatston units (AU.). Following the abdominalcomputed tomography (CT) scans, all patient s heights and weights were obtained from medicalreports. Their body mass indexes (BMI) were calculated by dividing these two variables. Patientswere then grouped according to World Health Organization Expert Committee on Physical Status.BMIs under 25 kg/m2were categorized as normal weighted group (Group 1), BMIs between 25 - 29.9 kg/m2were grouped as overweighted (Group 2), and BMIs equal or over 30 kg/m2wereaccepted as obese group (Group 3).Results: Mean BMIs -AaCs in Group 1, 2, and 3 were found to be 22.3 ±1.6 -254 ±597 AU,27.4 ±1.4 -244.5 ±496.7 AU, 33.4 ±2.6 -368.2 ±604.5 AU, respectively.Conclusions: According to correlation analysis, no significant correlation was observed betweenBMI and AaCs in these subgroups.

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1. Flegal KM, Carroll MD, Kuczmarski RJ. Overweight and obesity in the United States: prevalence and trends. Int J Obes Relat Metab Disord 1998; 22: 39-47.
2. Flegal KM, Carroll MD, Ogden CL. Prevalence and trends in obesity among US adults. JAMA 2002; 2881723-7.
3. Ogden CL, Carroll MD, Curtin LR. Prevalence of overweight and obesity in the United States. JAMA 2006; 295: 1549-55.
4. Wong ND, Hsu JC, Detrano RC. Coronary artery calcium evaluation by electron beam computed tomography and its relation to new cardiovascular events. Am J Cardiol 2000; 86: 495-8.
5. Arad Y, Spadaro LA, Goodman K. Predictive value of electron beam computed tomography of the coronary arteries. 19-month follow-up of 1173 asymptomatic subjects. Circulation 1996; 93: 1951-3.
6. Detrano R, Guerci AD, Carr JJ. Coronary calcium as a predictor of coronary events in four racial or ethnic groups. N Engl J Med 2008; 358: 1336-45.
7. Poirier P, Giles TD, Bray GA. Obesity and cardiovascular disease: pathophysiology, evaluation and effect of weight loss: an update of the 1997 American Heart Association scientific statement on obesity and heart disease from the Obesity Committee of the Council on Nutrition, physical activity, and metabolism. Circulation 2006; 113: 898-918.
8. Rosengren A, Wedel H, Wilhelmsen L. Body weight and weight gain during adult life in men in relation to coronary heart disease and mortality. A prospective population study. Eur Heart J 1999; 20: 269-77.
9. Breeze E, Clarke R, Shipley MJ. Cause-specifi mortality in old age in relation to body mass index in middle age and in old age: follow- up of the Whitehall cohort of male civil servants. Int J Epidemiol 2006; 35: 169-78.
10. Bamia C, Halkjaer J, Lagiou P. Weight change in later life and risk of death amongst the elderly: the European prospective investigation into cancer and nutrition-elderly network on ageing and health study. J Intern Med 2010; 268: 133-44.
11. Jelic S, Bartels MN, Mateika JH. Arterial stiffness increases during obstructive sleep apneas. Sleep 2002; 25: 850-5.
12. Hall JE. The kidney, hypertension, and obesity. Hypertension 2003; 41: 625-33.
13. Walsh CR, Cupples LA, Levy D. Abdominal aortic calcific deposits are associated with increased risk for congestive heart failure: the Framingham Heart Study. Am Heart J 2002; 144: 733-9.
14. World Health Organization. Physical status: the use and interpretation of anthropometry. Report of a WHO Expert Committee.In: World Health Organization technical report series 1995; 854: 1- 452.
15. Wexler L, Brundage B, Crouse J. Coronary artery calcification: pathophysiology, epidemiology, imaging methods, and clinical im- plications: a statement for health professionals from the American Heart Association Writing Group. Circulation 1996; 94: 1175-92.
16. Rumberger JA, Simons DB, Fitz- patrick LA. Coronary artery calcium area by electron-beam computed tomography and coronary atherosclerotic plaque area: a histopathologic correlative study. Circulation 1995; 92: 2157-62.
17. Simon A, Giral P, Levenson J. Ex- tracoronary atherosclerotic plaque at multiple sites and total coronary calcification deposit in asymptomatic men: association with coronary risk profile. Circulation 1995; 92: 1414-21.
18. Allison MA, Criqui MH, Wright CM: Patterns and risk factors for systemic calcified atherosclerosis. Arterioscler Thromb Vasc Biol 2004; 24: 331-6.
19. Hoff JA, Chomka EV, Krainik AJ. Age and gender distributions of coronary artery calcium detected by electron beam tomography in 35,246 adults. Am J Cardiol 2001; 87: 1335-9.
20. Teale C, Romaniuk C, Mulley G. Calcification on chest radiographs: the association with age. Age Age- ing 1989; 18: 333-6.
21. Gorich J, Zuna I, Merle M. Aortic calcification in CT: correlation with risk factors and cardiovascular diseases. Radiologe 1989; 29: 614.
22. Iribarren C, Sidney S, Sternfeld B. Calcification of the aortic arch: risk factors and association with coronary heart disease, stroke, and peripheral vascular disease. JAMA 2000; 283: 2810-5.
23. Pacchioni A, Rossi A, Benfari G. A higher body mass index is associated with reduced prevalence of unstable atherosclerotic plaque: a possible explanation of the obesity paradox.Int J Cardiol 2013; 168: 2912-3.