Ali Emre ATICI, Şükrü TAŞ, Feza EKİZ, Mustafa DUMAN, Musa AKOĞLU, İlter ÖZER, Erol Birol BOSTANCI, M. Fatih AYDIN

Caroli hastalığı: Olgu sunumu

Caroli hastalığı intrahepatik safra yollarının kistik dilatasyonu ile karakterize, konjenital, nadir görülen bir hastalığıdır. Caroli hastalığının klinik özellikleri hepatolitiazis veya bakteriyel kolanjite bağlı olarak gelişen sarılık, sağ üst kadran ağrısı, ateşi kapsamaktadır. Endoskopik veya perkutan kolanjiografi geleneksel tanı yöntemidir, fakat günümüzde manyetik rezonans kolanjiopankreatografi tercih edilen tanı aracı olarak ortaya çıkmıştır. Caroli hastalığının tedavisi; kolanjit için antibiyoterapi ve destek tedavisi, hepatolitiazis için ursodeoksikolik asit tedavisini kapsamaktadır. Karaciğerin tek lobunu tutan lokalize Caroli hastalığında cerrahi rezeksiyon başarı ile uygulanmaktadır. Diffüz tutulumlarında ise ortotopik karaciğer nakli seçilecek tedavi olmalıdır. Biz burada 58 yaşında, 3 yıldır karın ağrısı şikayeti, kolanjit atakları olan ve sonuçta cerrahi rezeksiyon ile tedavi edilen Caroli olgusunu sunduk.

Caroli’s disease: Case report

Caroli's disease is a rare congenital disease of the liver characterized by cystic dilatation of the intrahepatic bile duct. The clinical features of Caroli's disease include jaundice, right upper abdominal pain and fever due to the associated complications of hepatolithiasis or bacterial cholangitis. Endoscopic or percutaneous cholangiography is the traditional method of diagnosis, but nowadays magnetic resonance cholangiopancreatography is emerging as the diagnostic modality of choice. The treatment for Caroli's disease includes supportive care with antibiotics for cholangitis and ursodeoxycholic acid for hepatolithiasis. Surgical resection has been used successfully in patients with monolobar disease. For patients with diffuse involvement, the treatment of choice is orthotopic liver transplantation. In this article, we report a 58 years – old male patient with Caroli’s disease. The patient had abdominal pain and episodes of cholangitis for 3 years and finally, he was treated with surgical resection.

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